ENSDARG00000038743


Danio rerio

Features
Gene ID: ENSDARG00000038743
  
Biological name :copb2
  
Synonyms : coatomer protein complex, subunit beta 2 / copb2
  
Possible biological names infered from orthology : Coatomer subunit beta / O55029 / P35606
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 38997357
Gene end: 39015130
  
Corresponding Affymetrix probe sets: Dr.14625.1.A1_at (Zebrafish Array)   Dr.14625.1.A1_s_at (Zebrafish Array)   Dr.14687.1.A1_at (Zebrafish Array)   NM_001001940_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000044330
NCBI entrez gene - 114454     See in Manteia.
RefSeq - NM_001001940
RefSeq Peptide - NP_001001940
swissprot - B0R171
ZFIN ID - ZDB-GENE-010724-7
Ensembl - ENSDARG00000038743
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COPB2ENSGALG00000005357Gallus gallus
 COPB2ENSG00000184432Homo sapiens
 Copb2ENSMUSG00000032458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR006692  Coatomer, WD associated region
 IPR011044  Quinoprotein amine dehydrogenase, beta chain-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016453  Coatomer beta" subunit (COPB2)
 IPR017986  WD40-repeat-containing domain
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0061053 somite development IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030126 COPI vesicle coat IBA
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord quality , abnormal
notochord structure , abnormal
notochord poorly differentiated , abnormal
notochord undifferentiated , abnormal
notochord decreased length , abnormal
notochord apoptotic , abnormal
notochord basement membrane decreased thickness , abnormal
notochord basement membrane disorganized , abnormal
notochord basal lamina absent , abnormal
notochord endoplasmic reticulum swollen , abnormal
notochord Golgi apparatus structure , abnormal
notochord cell structure , abnormal
Show

 ZFA:0000155 somite somite size , abnormal
somite condensed , abnormal
somite morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism degenerate , abnormal
whole organism shape , abnormal
whole organism decreased length , abnormal
whole organism viability , abnormal
Show

 ZFA:0001115 trunk trunk melanosome absent , abnormal
Show

 ZFA:0009091 melanocyte melanocyte melanosome absent , abnormal
Show

 ZFA:0009114 muscle cell muscle cell endoplasmic reticulum swollen , abnormal
muscle cell Golgi apparatus structure , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr