ENSDARG00000038867


Danio rerio

Features
Gene ID: ENSDARG00000038867
  
Biological name :shhb
  
Synonyms : Q90419 / shhb / sonic hedgehog b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 30050541
Gene end: 30055432
  
Corresponding Affymetrix probe sets: Dr.5753.1.S1_at (Zebrafish Array)   NM_131199_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000056746
NCBI entrez gene - 30444     See in Manteia.
RefSeq - NM_131199
RefSeq Peptide - NP_571274
swissprot - A0A0B5JJZ7
swissprot - Q90419
ZFIN ID - ZDB-GENE-980526-41
Ensembl - ENSDARG00000038867
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
shha / Q92008 / sonic hedgehog aENSDARG0000006856770
ihha / Indian hedgehog homolog a / IHH* / Q14623* / P97812* / indian hedgehog*ENSDARG0000005873358
ihhb / Indian hedgehog homolog b / IHH* / Q14623* / P97812* / indian hedgehog*ENSDARG0000005881556
dhh / desert hedgehog / O43323* / Q61488* / Desert hedgehog protein Desert hedgehog protein N-product Desert hedgehog protein C-product*ENSDARG0000003706244


Protein motifs (from Interpro)
Interpro ID Name
 IPR000320  Hedgehog, N-terminal signalling domain
 IPR001657  Hedgehog protein
 IPR001767  Hedgehog protein, Hint domain
 IPR003586  Hint domain C-terminal
 IPR003587  Hint domain N-terminal
 IPR009045  Hedgehog signalling/DD-peptidase zinc-binding domain superfamily
 IPR028992  Hedgehog/Intein (Hint) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0030900 forebrain development IMP
 biological_processGO:0042063 gliogenesis IGI
 biological_processGO:0048663 neuron fate commitment IGI
 biological_processGO:0048702 embryonic neurocranium morphogenesis IGI
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IGI
 biological_processGO:0055002 striated muscle cell development IGI
 biological_processGO:0060956 endocardial cell differentiation IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye fused with eye , abnormal
Show

 ZFA:0000155 somite somite morphology , abnormal
somite U-shaped , abnormal
Show

 ZFA:0000217 inner ear inner ear wholly anterioralized , abnormal
Show

 ZFA:0000539 locus coeruleus locus coeruleus neuron decreased amount , abnormal
Show

 ZFA:0000558 posterior macula posterior macula aplastic , abnormal
Show

 ZFA:0001153 tooth placode tooth placode position , abnormal
Show

 ZFA:0001617 otolith otolith decreased size , abnormal
Show

 ZFA:0005409 pars superior ear pars superior ear has extra parts of type anterior crista , abnormal
Show

 ZFA:0009244 primary motor neuron primary motor neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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