ENSDARG00000039020


Danio rerio

Features
Gene ID: ENSDARG00000039020
  
Biological name :fbxo5
  
Synonyms : F-box protein 5 / fbxo5
  
Possible biological names infered from orthology : F-box only protein 5 / Q7TSG3 / Q9UKT4
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 46941930
Gene end: 46958802
  
Corresponding Affymetrix probe sets: Dr.5345.1.S1_at (Zebrafish Array)   NM_001003869_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000101772
Ensembl peptide - ENSDARP00000144846
Ensembl peptide - ENSDARP00000056961
NCBI entrez gene - 445392     See in Manteia.
RefSeq - NM_001003869
RefSeq Peptide - NP_001003869
swissprot - F1QJI8
swissprot - F1QTH3
ZFIN ID - ZDB-GENE-030131-4027
Ensembl - ENSDARG00000039020
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FBXO5ENSGALG00000013607Gallus gallus
 FBXO5ENSG00000112029Homo sapiens
 Fbxo5ENSMUSG00000019773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fbxo43 / F-box protein 43 / Q4G163*ENSDARG0000010418618


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR002867  IBR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of APC/C activators between G1/S and early anaphase
Phosphorylation of Emi1
Mitotic Metaphase/Anaphase Transition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
brain surface feature shape , abnormal
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 ZFA:0000012 central nervous system central nervous system neuron decreased amount , abnormal
central nervous system necrotic , abnormal
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 ZFA:0000019 epiphysis epiphysis decreased size , abnormal
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 ZFA:0000022 floor plate floor plate cell increased size , abnormal
floor plate cell separated from floor plate cell, abnormal
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 ZFA:0000029 hindbrain hindbrain dorsal region disorganized , abnormal
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 ZFA:0000031 hypochord hypochord cell increased size , abnormal
hypochord cell separated from hypochord cell, abnormal
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 ZFA:0000048 olfactory placode olfactory placode decreased size , abnormal
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 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
eye shape , abnormal
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 ZFA:0000109 forebrain forebrain ventral region structure , abnormal
Show

 ZFA:0000132 neural plate neural plate increased width , abnormal
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 ZFA:0000140 pancreas pancreas decreased size , abnormal
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 ZFA:0000155 somite somite deformed , abnormal
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 ZFA:0000168 anterior macula anterior macula has fewer parts of type auditory receptor cell , abnormal
anterior macula unstratified , abnormal
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 ZFA:0000421 reticular formation reticular formation structure , abnormal
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 ZFA:0000778 spinal cord interneuron spinal cord interneuron decreased amount , abnormal
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 ZFA:0001058 caudal fin caudal fin curved ventral , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism bent , abnormal
whole organism deformed , abnormal
whole organism nucleus increased size , abnormal
whole organism necrotic , abnormal
whole organism anterior-posterior axis decreased length , abnormal
whole organism viability , abnormal
whole organism cell polyploid , abnormal
whole organism cell tetraploid , abnormal
whole organism cell endopolyploid , abnormal
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 ZFA:0001104 pharyngeal endoderm pharyngeal endoderm decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head surface feature shape , abnormal
head cell death increased process quality , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk bent , abnormal
trunk degenerate , abnormal
trunk curved ventral , abnormal
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 ZFA:0001117 post-vent region post-vent region quality , abnormal
Show

 ZFA:0001157 posterior lateral line primordium posterior lateral line primordium decreased size , abnormal
posterior lateral line primordium mislocalised , abnormal
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 ZFA:0001202 optic cup optic cup hypoplastic , abnormal
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 ZFA:0001260 endocrine pancreas endocrine pancreas decreased size , abnormal
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 ZFA:0001261 ventricular system ventricular system structure, cavities , abnormal
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 ZFA:0001558 pronephric tubule pronephric tubule morphology , abnormal
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 ZFA:0001679 solid lens vesicle solid lens vesicle decreased size , abnormal
solid lens vesicle protruding out of immature eye , abnormal
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 ZFA:0001692 hindbrain commissure hindbrain commissure axon disorganized , abnormal
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 ZFA:0005227 protoneuromast protoneuromast absent , abnormal
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 ZFA:0007038 anterior neural tube anterior neural tube decreased width , abnormal
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 ZFA:0009000 cell cell increased size , abnormal
cell polyploid , abnormal
cell chromosome polyploid , abnormal
cell chromosome undivided , abnormal
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 ZFA:0009048 granulocyte granulocyte decreased amount , abnormal
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 ZFA:0009052 motor neuron motor neuron decreased amount , abnormal
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 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009141 macrophage macrophage decreased amount , abnormal
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 ZFA:0009149 Mauthner neuron Mauthner neuron axon decreased amount , abnormal
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 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
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 ZFA:0009244 primary motor neuron primary motor neuron decreased amount , abnormal
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 ZFA:0009248 neuron neuron increased size , abnormal
neuron microtubule molecular quality , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte increased size , abnormal
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 ZFA:0009324 myeloid cell myeloid cell decreased amount , abnormal
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 ZFA:0009325 erythroid lineage cell erythroid lineage cell increased variability of size , abnormal
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 ZFA:0009327 neutrophil neutrophil decreased amount , abnormal
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 ZFA:0009356 myeloid lineage restricted progenitor cell myeloid lineage restricted progenitor cell decreased amount , abnormal
myeloid lineage restricted progenitor cell increased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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