ENSDARG00000039970


Danio rerio

Features
Gene ID: ENSDARG00000039970
  
Biological name :cnr2
  
Synonyms : cannabinoid receptor 2 / cnr2
  
Possible biological names infered from orthology : P34972 / P47936
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 33109496
Gene end: 33119626
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000058472
Ensembl peptide - ENSDARP00000137617
swissprot - F1R8K4
ZFIN ID - ZDB-GENE-040702-7
Ensembl - ENSDARG00000039970
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CNR2ENSGALG00000004120Gallus gallus
 CNR2ENSG00000188822Homo sapiens
 Cnr2ENSMUSG00000062585Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cnr1 / cannabinoid receptor 1 / P21554* / P47746* / Mus musculus cannabinoid receptor 1 (brain) (Cnr1), transcript variant 2, mRNA.*ENSDARG0000000902039
gpr186 / G protein-coupled receptor 186ENSDARG0000009486021
s1pr1 / sphingosine-1-phosphate receptor 1 / O08530* / P21453*ENSDARG0000004269021
s1pr4 / sphingosine-1-phosphate receptor 4 / O95977* / Q9Z0L1*ENSDARG0000007485120
gpr12 / G protein-coupled receptor 12 / P35412* / P47775*ENSDARG0000006293420
lpar2a / lysophosphatidic acid receptor 2a / LPAR2* / Q9HBW0* / lysophosphatidic acid receptor 2*ENSDARG0000004233819
s1pr2 / Q9I8K8 / sphingosine-1-phosphate receptor 2 / O95136*ENSDARG0000003654819
gpr6 / G protein-coupled receptor 6 / P46095*ENSDARG0000005240019
s1pr5a / sphingosine-1-phosphate receptor 5aENSDARG0000004052619
lpar2b / lysophosphatidic acid receptor 2b / LPAR2* / Q9HBW0* / lysophosphatidic acid receptor 2*ENSDARG0000004256119
s1pr3a / sphingosine-1-phosphate receptor 3a / S1PR3* / Q9Z0U9* / Q99500* / sphingosine-1-phosphate receptor 3*ENSDARG0000004247018
lpar3 / lysophosphatidic acid receptor 3 / Q9UBY5*ENSDARG0000010181418
gpr185a / G protein-coupled receptor 185 aENSDARG0000006040018
gpr185b / G protein-coupled receptor 185 bENSDARG0000003656018
s1pr5b / sphingosine-1-phosphate receptor 5b / S1PR5* / Q9H228* / Q91X56* / sphingosine-1-phosphate receptor 5*ENSDARG0000005219217
lpar1 / lysophosphatidic acid receptor 1 / P61793* / Q92633*ENSDARG0000009984015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002230  Cannabinoid receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006555 methionine metabolic process IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0035701 hematopoietic stem cell migration IDA
 biological_processGO:0038171 cannabinoid signaling pathway IEA
 biological_processGO:0060218 hematopoietic stem cell differentiation IMP
 biological_processGO:0097241 hematopoietic stem cell migration to bone marrow IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004949 cannabinoid receptor activity IEA


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000036 liver and biliary system liver and biliary system spatial pattern , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
Show

 ZFA:0000123 liver liver decreased size , abnormal
liver lipid increased amount , abnormal
liver lipid amount , ameliorated
liver cysteine decreased amount , abnormal
liver S-adenosyl-L-methionine decreased amount , abnormal
liver S-adenosyl-L-homocysteine decreased amount , abnormal
liver methionine decreased amount , abnormal
liver homocysteine decreased amount , abnormal
liver serine decreased amount , abnormal
liver triglyceride increased amount , abnormal
liver homoserine decreased amount , abnormal
liver size , ameliorated
liver decreased distribution , abnormal
liver cell proliferation decreased rate , abnormal
Show

 ZFA:0000208 gall bladder gall bladder lipase activity absent , abnormal
Show

 ZFA:0000242 male organism male organism liver decreased amount , abnormal
Show

 ZFA:0001338 intestine intestine lipase activity decreased occurrence , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0005165 common bile duct common bile duct decreased branchiness , abnormal
common bile duct morphology , abnormal
common bile duct branchiness , ameliorated
Show

 ZFA:0005857 bile bile accumulation liver , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte morphology , abnormal
hepatocyte morphology , ameliorated
hepatocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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