ENSDARG00000042690


Danio rerio

Features
Gene ID: ENSDARG00000042690
  
Biological name :s1pr1
  
Synonyms : s1pr1 / sphingosine-1-phosphate receptor 1
  
Possible biological names infered from orthology : O08530 / P21453
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 16038495
Gene end: 16042243
  
Corresponding Affymetrix probe sets: Dr.25683.5.A1_at (Zebrafish Array)   Dr.3282.1.S1_at (Zebrafish Array)   NM_131691_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062632
NCBI entrez gene - 64617     See in Manteia.
RefSeq - NM_131691
RefSeq Peptide - NP_571766
swissprot - Q1LV63
ZFIN ID - ZDB-GENE-001228-2
Ensembl - ENSDARG00000042690
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 S1PR1ENSGALG00000005208Gallus gallus
 S1PR1ENSG00000170989Homo sapiens
 S1pr1ENSMUSG00000045092Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
s1pr5a / sphingosine-1-phosphate receptor 5aENSDARG0000004052648
s1pr3a / sphingosine-1-phosphate receptor 3a / S1PR3* / Q9Z0U9* / Q99500* / sphingosine-1-phosphate receptor 3*ENSDARG0000004247047
s1pr2 / Q9I8K8 / sphingosine-1-phosphate receptor 2 / O95136*ENSDARG0000003654844
s1pr5b / sphingosine-1-phosphate receptor 5b / S1PR5* / Q9H228* / Q91X56* / sphingosine-1-phosphate receptor 5*ENSDARG0000005219243
s1pr4 / sphingosine-1-phosphate receptor 4 / O95977* / Q9Z0L1*ENSDARG0000007485141
lpar2b / lysophosphatidic acid receptor 2b / LPAR2* / Q9HBW0* / lysophosphatidic acid receptor 2*ENSDARG0000004256131
lpar2a / lysophosphatidic acid receptor 2a / LPAR2* / Q9HBW0* / lysophosphatidic acid receptor 2*ENSDARG0000004233830
lpar3 / lysophosphatidic acid receptor 3 / Q9UBY5*ENSDARG0000010181430
lpar1 / lysophosphatidic acid receptor 1 / P61793* / Q92633*ENSDARG0000009984025
gpr12 / G protein-coupled receptor 12 / P35412* / P47775*ENSDARG0000006293423
gpr6 / G protein-coupled receptor 6 / P46095*ENSDARG0000005240023
cnr1 / cannabinoid receptor 1 / P21554* / P47746* / Mus musculus cannabinoid receptor 1 (brain) (Cnr1), transcript variant 2, mRNA.*ENSDARG0000000902023
cnr2 / cannabinoid receptor 2 / P34972* / P47936*ENSDARG0000003997022
gpr186 / G protein-coupled receptor 186ENSDARG0000009486020
gpr185a / G protein-coupled receptor 185 aENSDARG0000006040020
gpr185b / G protein-coupled receptor 185 bENSDARG0000003656018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000987  EDG-1 sphingosine 1-phosphate receptor
 IPR004061  Sphingosine 1-phosphate receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003376 sphingosine-1-phosphate signaling pathway IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0038036 sphingosine-1-phosphate receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Lysosphingolipid and LPA receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta endothelial cell decreased amount , abnormal
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 ZFA:0000029 hindbrain hindbrain malformed , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000060 prechordal plate prechordal plate decreased length , abnormal
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 ZFA:0000114 heart heart physical object quality , abnormal
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 ZFA:0000117 hypoblast hypoblast mesodermal cell decreased speed , abnormal
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 ZFA:0000131 neural keel neural keel decreased length , abnormal
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 ZFA:0000152 retina retina filopodium increased amount , abnormal
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 ZFA:0000477 posterior cardinal vein posterior cardinal vein endothelial cell decreased amount , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel decreased length , abnormal
intersegmental vessel shortened , abnormal
intersegmental vessel morphology , abnormal
intersegmental vessel endothelial cell decreased amount , abnormal
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 ZFA:0001286 caudal vein plexus caudal vein plexus endothelial cell has extra parts of type endothelial cell filopodium, abnormal
caudal vein plexus morphology , abnormal
caudal vein plexus decreased length , abnormal
caudal vein plexus decreased width , abnormal
caudal vein plexus decreased area , abnormal
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 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 decreased length , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel disorganized , abnormal
dorsal longitudinal anastomotic vessel endothelial cell decreased amount , abnormal
Show

 ZFA:0005035 subintestinal vein subintestinal vein dilated , abnormal
subintestinal vein has extra parts of type angiogenic sprout , abnormal
subintestinal vein morphology , abnormal
subintestinal vein deformed , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte increased accumulation blood island , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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