ENSDARG00000040295


Danio rerio

Features
Gene ID: ENSDARG00000040295
  
Biological name :apoeb
  
Synonyms : apoeb / apolipoprotein Eb / O42364
  
Possible biological names infered from orthology : APOE / apolipoprotein E / P02649 / P08226
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 23960744
Gene end: 23963461
  
Corresponding Affymetrix probe sets: Dr.1246.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000119141
Ensembl peptide - ENSDARP00000155792
Ensembl peptide - ENSDARP00000058964
NCBI entrez gene - 30314     See in Manteia.
RefSeq - XM_005158086
RefSeq Peptide - NP_571173
swissprot - E9QBB8
swissprot - O42364
ZFIN ID - ZDB-GENE-980526-368
Ensembl - ENSDARG00000040295
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APOEENSG00000130203Homo sapiens
 ApoeENSMUSG00000002985Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
apoea / apolipoprotein Ea / APOE* / P02649* / P08226* / apolipoprotein E*ENSDARG0000010200442


Protein motifs (from Interpro)
Interpro ID Name
 IPR000074  Apolipoprotein A/E


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006695 cholesterol biosynthetic process IBA
 biological_processGO:0006707 cholesterol catabolic process IBA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0010873 positive regulation of cholesterol esterification IBA
 biological_processGO:0019433 triglyceride catabolic process IBA
 biological_processGO:0030516 regulation of axon extension IBA
 biological_processGO:0031102 neuron projection regeneration IBA
 biological_processGO:0032374 regulation of cholesterol transport IBA
 biological_processGO:0033344 cholesterol efflux IBA
 biological_processGO:0033700 phospholipid efflux IBA
 biological_processGO:0034372 very-low-density lipoprotein particle remodeling IBA
 biological_processGO:0034380 high-density lipoprotein particle assembly IBA
 biological_processGO:0042157 lipoprotein metabolic process IEA
 biological_processGO:0042159 lipoprotein catabolic process IBA
 biological_processGO:0042632 cholesterol homeostasis IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IBA
 biological_processGO:0043691 reverse cholesterol transport IBA
 biological_processGO:0046889 positive regulation of lipid biosynthetic process IBA
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity IBA
 biological_processGO:1900221 regulation of amyloid-beta clearance IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0034363 intermediate-density lipoprotein particle IBA
 cellular_componentGO:0034364 high-density lipoprotein particle IBA
 cellular_componentGO:0042627 chylomicron IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0001540 amyloid-beta binding IBA
 molecular_functionGO:0005543 phospholipid binding IBA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IBA
 molecular_functionGO:0017127 cholesterol transporter activity IBA
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IBA
 molecular_functionGO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity IBA
 molecular_functionGO:0070326 very-low-density lipoprotein particle receptor binding IBA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Chylomicron remodeling
Chylomicron clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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