ENSDARG00000040557


Danio rerio

Features
Gene ID: ENSDARG00000040557
  
Biological name :exosc5
  
Synonyms : exosc5 / exosome component 5
  
Possible biological names infered from orthology : Exosome complex component RRP46 / Q9CRA8 / Q9NQT4
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 36060295
Gene end: 36066087
  
Corresponding Affymetrix probe sets: Dr.17708.1.S1_at (Zebrafish Array)   NM_001045352_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000059351
Ensembl peptide - ENSDARP00000119735
NCBI entrez gene - 751632     See in Manteia.
RefSeq - NM_001045352
RefSeq Peptide - NP_001038817
swissprot - Q1LVM3
swissprot - Q1LVM4
ZFIN ID - ZDB-GENE-060503-675
Ensembl - ENSDARG00000040557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EXOSC5ENSG00000077348Homo sapiens
 Exosc5ENSMUSG00000061286Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001247  Exoribonuclease, phosphorolytic domain 1
 IPR015847  Exoribonuclease, phosphorolytic domain 2
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027408  PNPase/RNase PH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016075 rRNA catabolic process IBA
 biological_processGO:0031125 rRNA 3"-end processing IBA
 biological_processGO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3"-5" IBA
 biological_processGO:0034475 U4 snRNA 3"-end processing IBA
 biological_processGO:0071028 nuclear mRNA surveillance IBA
 biological_processGO:0071051 polyadenylation-dependent snoRNA 3"-end processing IBA
 cellular_componentGO:0000176 nuclear exosome (RNase complex) IBA
 cellular_componentGO:0000177 cytoplasmic exosome (RNase complex) IBA
 cellular_componentGO:0005730 nucleolus IBA


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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