Manteia

ENSDARG00000040917

Danio rerio

Features

Gene ID:	ENSDARG00000040917

Biological name :	cbfb

Synonyms :	cbfb / core-binding factor, beta subunit

Possible biological names infered from orthology :	Core-binding factor subunit beta / Q08024 / Q13951

Species:	Danio rerio

Chr. number:	18
Strand:	1
Band:
Gene start:	22994113
Gene end:	23072665

Corresponding Affymetrix probe sets:	DrAffx.1.14.S1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000138911 Ensembl peptide - ENSDARP00000142460 Ensembl peptide - ENSDARP00000142411 Ensembl peptide - ENSDARP00000142352 Ensembl peptide - ENSDARP00000142316 Ensembl peptide - ENSDARP00000142061 Ensembl peptide - ENSDARP00000059960 NCBI entrez gene - 30744 See in Manteia. swissprot - A0A140LGT1 swissprot - A0A0B4PJ32 swissprot - A0A0B4PIS7 swissprot - A0A0B4P506 swissprot - A0A0B4P4A4 swissprot - Q98U16 ZFIN ID - ZDB-GENE-980526-440 Ensembl - ENSDARG00000040917

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR003417	Core-binding factor, beta subunit

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006357	regulation of transcription by RNA polymerase II	IC
biological_process	GO:0030097	hemopoiesis	IMP
biological_process	GO:0045214	sarcomere organization	IMP
biological_process	GO:0048769	sarcomerogenesis	IMP
biological_process	GO:0060047	heart contraction	IMP
cellular_component	GO:0005634	nucleus	IDA
cellular_component	GO:0016513	core-binding factor complex	IPI
cellular_component	GO:0030018	Z disc	IDA
molecular_function	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding	IC
molecular_function	GO:0003677	DNA binding	IPI
molecular_function	GO:0003712	transcription coregulator activity	IDA
molecular_function	GO:0003713	transcription coactivator activity	IEA
molecular_function	GO:0046982	protein heterodimerization activity	IPI

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000009	cardiac ventricle	cardiac ventricle dilated , abnormal	Show
ZFA:0000114	heart	heart non-functional , abnormal	Show
ZFA:0000295	trigeminal ganglion	trigeminal ganglion absent , abnormal trigeminal ganglion increased amount , abnormal trigeminal ganglion decreased amount , abnormal	Show
ZFA:0000471	atrium	atrium dilated , abnormal	Show
ZFA:0005277	skeletal muscle	skeletal muscle decreased functionality , abnormal	Show
ZFA:0009115	skeletal muscle cell	skeletal muscle cell has fewer parts of type skeletal muscle cell myosin filament, abnormal	Show
ZFA:0009150	Rohon-Beard neuron	Rohon-Beard neuron absent , abnormal Rohon-Beard neuron increased amount , abnormal Rohon-Beard neuron decreased amount , abnormal	Show
ZFA:0009316	cardiac muscle cell	cardiac muscle cell has fewer parts of type cardiac muscle cell myosin filament, abnormal cardiac muscle cell intercalated disc malformed , abnormal cardiac muscle cell sarcomere decreased thickness , abnormal cardiac muscle cell Z disc malformed , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr