ENSDARG00000040946


Danio rerio

Features
Gene ID: ENSDARG00000040946
  
Biological name :olig2
  
Synonyms : olig2 / oligodendrocyte lineage transcription factor 2
  
Possible biological names infered from orthology : oligodendrocyte transcription factor 2 / Q13516 / Q9EQW6
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 32751428
Gene end: 32753535
  
Corresponding Affymetrix probe sets: Dr.3920.1.S1_at (Zebrafish Array)   NM_178100_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000060005
NCBI entrez gene - 325288     See in Manteia.
RefSeq - NM_178100
RefSeq Peptide - NP_835201
swissprot - A8WIQ8
ZFIN ID - ZDB-GENE-030131-4013
Ensembl - ENSDARG00000040946
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OLIG2ENSGALG00000031010Gallus gallus
 OLIG2ENSG00000205927Homo sapiens
 Olig2ENSMUSG00000039830Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
olig4 / oligodendrocyte transcription factor 4ENSDARG0000005261038
olig1 / oligodendrocyte transcription factor 1 / Q8TAK6* / Q9JKN5*ENSDARG0000004094826
bhlhe22 / basic helix-loop-helix family, member e22 / Q8NFJ8*ENSDARG0000005803925
bhlhe23 / basic helix-loop-helix family, member e23 / Q8BGW3* / Q8NDY6* / Class E basic helix-loop-helix protein 23 *ENSDARG0000003758823
si:ch211-196c10.13ENSDARG0000009675618


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032658  Oligodendrocyte transcription factor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007400 neuroblast fate determination IMP
 biological_processGO:0007403 glial cell fate determination IMP
 biological_processGO:0014003 oligodendrocyte development IMP
 biological_processGO:0021514 ventral spinal cord interneuron differentiation IMP
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IMP
 biological_processGO:0021522 spinal cord motor neuron differentiation IMP
 biological_processGO:0021742 abducens nucleus development IMP
 biological_processGO:0021754 facial nucleus development IMP
 biological_processGO:0021778 oligodendrocyte cell fate specification IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0050769 positive regulation of neurogenesis IMP
 biological_processGO:0071542 dopaminergic neuron differentiation IMP
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain glioblast (sensu Vertebrata) decreased amount , abnormal
Show

 ZFA:0000075 spinal cord spinal cord motor neuron decreased amount , abnormal
spinal cord GABAergic neuron amount , abnormal
spinal cord lacks all parts of type primary motor neuron , abnormal
spinal cord lacks parts or has fewer parts of type oligodendrocyte , abnormal
Show

 ZFA:0000206 facial nerve motor nucleus facial nerve motor nucleus motor neuron mislocalised , abnormal
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 ZFA:0000310 cranial nerve VI cranial nerve VI motor neuron decreased amount , abnormal
Show

 ZFA:0000778 spinal cord interneuron spinal cord interneuron cellular quality , abnormal
Show

 ZFA:0001256 lateral floor plate lateral floor plate Kolmer-Agduhr neuron cellular quality , abnormal
Show

 ZFA:0005034 parachordal vessel parachordal vessel immature , abnormal
parachordal vessel venous endothelial cell migration involved in lymph vessel development arrested , abnormal
Show

 ZFA:0009052 motor neuron motor neuron lacks parts or has fewer parts of type motor neuron axon, abnormal
Show

 ZFA:0009076 oligodendrocyte oligodendrocyte decreased amount , abnormal
Show

 ZFA:0009301 dopaminergic neuron dopaminergic neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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