ENSG00000205927


Homo sapiens

Features
Gene ID: ENSG00000205927
  
Biological name :OLIG2
  
Synonyms : OLIG2 / oligodendrocyte transcription factor 2 / Q13516
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.11
Gene start: 33025845
Gene end: 33029196
  
Corresponding Affymetrix probe sets: 213824_at (Human Genome U133 Plus 2.0 Array)   213825_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000331040
Ensembl peptide - ENSP00000391183
Ensembl peptide - ENSP00000371794
NCBI entrez gene - 10215     See in Manteia.
OMIM - 606386
RefSeq - NM_005806
RefSeq - XM_005260908
RefSeq Peptide - NP_005797
swissprot - C9J444
swissprot - Q13516
Ensembl - ENSG00000205927
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 olig2ENSDARG00000040946Danio rerio
 OLIG2ENSGALG00000031010Gallus gallus
 Olig2ENSMUSG00000039830Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OLIG3 / Q7RTU3 / oligodendrocyte transcription factor 3ENSG0000017746844
OLIG1 / Q8TAK6 / oligodendrocyte transcription factor 1ENSG0000018422127
Q8NFJ8 / BHLHE22 / basic helix-loop-helix family member e22ENSG0000018082826
Q8NDY6 / BHLHE23 / basic helix-loop-helix family member e23ENSG0000012553323


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032658  Oligodendrocyte transcription factor 2
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0021522 spinal cord motor neuron differentiation IEA
 biological_processGO:0021529 spinal cord oligodendrocyte cell differentiation IEA
 biological_processGO:0021530 spinal cord oligodendrocyte cell fate specification IEA
 biological_processGO:0021778 oligodendrocyte cell fate specification IEA
 biological_processGO:0021794 thalamus development IEA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0048663 neuron fate commitment IEA
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0048714 positive regulation of oligodendrocyte differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0071837 HMG box domain binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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