ENSG00000125533


Homo sapiens

Features
Gene ID: ENSG00000125533
  
Biological name :BHLHE23
  
Synonyms : basic helix-loop-helix family member e23 / BHLHE23 / Q8NDY6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.33
Gene start: 63005927
Gene end: 63007035
  
Corresponding Affymetrix probe sets: 234045_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359371
Ensembl peptide - ENSP00000480998
NCBI entrez gene - 128408     See in Manteia.
OMIM - 609331
RefSeq - NM_080606
RefSeq Peptide - NP_542173
swissprot - A0A087WXG3
swissprot - Q8NDY6
Ensembl - ENSG00000125533
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bhlhe23ENSDARG00000037588Danio rerio
 BHLHE23ENSGALG00000005718Gallus gallus
 Q8BGW3ENSMUSG00000045493Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NFJ8 / BHLHE22 / basic helix-loop-helix family member e22ENSG0000018082842
OLIG2 / Q13516 / oligodendrocyte transcription factor 2ENSG0000020592730
OLIG3 / Q7RTU3 / oligodendrocyte transcription factor 3ENSG0000017746827
OLIG1 / Q8TAK6 / oligodendrocyte transcription factor 1ENSG0000018422124


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032662  Class E basic helix-loop-helix protein 23
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046548 retinal rod cell development IEA
 biological_processGO:0046671 negative regulation of retinal cell programmed cell death IEA
 biological_processGO:0048050 post-embryonic eye morphogenesis IEA
 biological_processGO:0048468 cell development IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr