ENSG00000177468


Homo sapiens

Features
Gene ID: ENSG00000177468
  
Biological name :OLIG3
  
Synonyms : OLIG3 / oligodendrocyte transcription factor 3 / Q7RTU3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q23.3
Gene start: 137492202
Gene end: 137494250
  
Corresponding Affymetrix probe sets: 1556371_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356708
NCBI entrez gene - 167826     See in Manteia.
OMIM - 609323
RefSeq - NM_175747
RefSeq Peptide - NP_786923
swissprot - Q7RTU3
Ensembl - ENSG00000177468
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OLIG3ENSGALG00000013862Gallus gallus
 Olig3ENSMUSG00000045591Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OLIG2 / Q13516 / oligodendrocyte transcription factor 2ENSG0000020592753
Q8NFJ8 / BHLHE22 / basic helix-loop-helix family member e22ENSG0000018082829
OLIG1 / Q8TAK6 / oligodendrocyte transcription factor 1ENSG0000018422129
Q8NDY6 / BHLHE23 / basic helix-loop-helix family member e23ENSG0000012553324


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR032659  Oligodendrocyte transcription factor 3
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IEA
 biological_processGO:0021522 spinal cord motor neuron differentiation IEA
 biological_processGO:0097476 spinal cord motor neuron migration IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr