ENSDARG00000041870


Danio rerio

Features
Gene ID: ENSDARG00000041870
  
Biological name :ift172
  
Synonyms : ift172 / intraflagellar transport 172 / Q5RHH4
  
Possible biological names infered from orthology : Intraflagellar transport / Q6VH22 / Q9UG01
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 38837238
Gene end: 38900420
  
Corresponding Affymetrix probe sets: Dr.19771.1.A1_at (Zebrafish Array)   NM_001002312_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000061333
NCBI entrez gene - 432389     See in Manteia.
RefSeq - NM_001002312
RefSeq Peptide - NP_001002312
swissprot - Q5RHH4
ZFIN ID - ZDB-GENE-040827-1
Ensembl - ENSDARG00000041870
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IFT172ENSGALG00000016509Gallus gallus
 IFT172ENSG00000138002Homo sapiens
 Ift172ENSMUSG00000038564Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0032006 regulation of TOR signaling IMP
 biological_processGO:0045494 photoreceptor cell maintenance IMP
 biological_processGO:0048793 pronephros development IGI
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0060271 cilium assembly ISS
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0005930 axoneme IBA
 cellular_componentGO:0030992 intraciliary transport particle B ISS
 cellular_componentGO:0036064 ciliary basal body IBA
 cellular_componentGO:0042995 cell projection IEA


Pathways (from Reactome)
Pathway description
Hedgehog off state
Intraflagellar transport
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle cilium decreased length , abnormal
otic vesicle cilium decreased amount , abnormal
Show

 ZFA:0000107 eye eye quality , abnormal
Show

 ZFA:0000130 olfactory pit olfactory pit cilium truncated , abnormal
olfactory pit cilium shortened , abnormal
Show

 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer quality , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct dilated , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
pronephros quality , abnormal
Show

 ZFA:0000152 retina retina morphology , abnormal
Show

 ZFA:0000529 kidney kidney cystic , abnormal
Show

 ZFA:0000578 ceratohyal bone ceratohyal bone shape , abnormal
Show

 ZFA:0000737 cranium cranium morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism curved ventral , abnormal
whole organism hydrocephalic , abnormal
whole organism shape , abnormal
Show

 ZFA:0001115 trunk trunk curved ventral , abnormal
trunk curved , abnormal
trunk undulate , abnormal
Show

 ZFA:0001117 post-vent region post-vent region increased curvature , abnormal
post-vent region curved ventral , abnormal
Show

 ZFA:0001135 neural tube neural tube axoneme absent , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage hypoplastic , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer decreased thickness , abnormal
Show

 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer disorganized , abnormal
photoreceptor outer segment layer decreased size , abnormal
Show

 ZFA:0009154 eye photoreceptor cell eye photoreceptor cell photoreceptor outer segment absent , abnormal
eye photoreceptor cell photoreceptor inner segment membrane disorganized , abnormal
eye photoreceptor cell nucleus decreased length , abnormal
eye photoreceptor cell centriole displaced , abnormal
eye photoreceptor cell photoreceptor connecting cilium absent , abnormal
eye photoreceptor cell photoreceptor inner segment membrane displaced , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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