ENSDARG00000042824


Danio rerio

Features
Gene ID: ENSDARG00000042824
  
Biological name :nfe2l2a
  
Synonyms : nfe2l2a / nuclear factor, erythroid 2-like 2a
  
Possible biological names infered from orthology : NFE2L2 / nuclear factor, erythroid 2 like 2 / Nuclear factor erythroid 2-related factor 2 / Q16236 / Q60795
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 1654284
Gene end: 1683368
  
Corresponding Affymetrix probe sets: Dr.12684.1.S1_at (Zebrafish Array)   Dr.12684.1.S2_at (Zebrafish Array)   Dr.7230.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000062853
NCBI entrez gene - 360149     See in Manteia.
RefSeq - XM_005172511
swissprot - Q7ZVI2
ZFIN ID - ZDB-GENE-030723-2
Ensembl - ENSDARG00000042824
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NFE2L2ENSGALG00000009240Gallus gallus
 NFE2L2ENSG00000116044Homo sapiens
 Nfe2l2ENSMUSG00000015839Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nfe2l2b / nuclear factor, erythroid 2-like 2bENSDARG0000008969723
nfe2l1a / nuclear factor, erythroid 2-like 1a / NFE2L1* / Q14494* / Q61985* / nuclear factor, erythroid 2 like 1* / Nuclear factor erythroid 2-related factor 1 *ENSDARG0000003061621
nfe2 / nuclear factor, erythroid 2 / Q16621*ENSDARG0000002060621
nfe2l3 / nuclear factor, erythroid 2-like 3 / Q9Y4A8*ENSDARG0000001981016
bach2b / BTB and CNC homology 1, basic leucine zipper transcription factor 2b / BACH2* / P97303* / Q9BYV9* / BTB domain and CNC homolog 2* / Transcription regulator protein BACH2 *ENSDARG0000000407414
bach2a / BTB and CNC homology 1, basic leucine zipper transcription factor 2a / BACH2* / P97303* / Q9BYV9* / BTB domain and CNC homolog 2* / Transcription regulator protein BACH2 *ENSDARG0000003656914
bach1a / BTB and CNC homology 1, basic leucine zipper transcription factor 1 a / BACH1* / O14867* / P97302* / BTB domain and CNC homolog 1* / Transcription regulator protein BACH1 *ENSDARG0000006255312
bach1b / BTB and CNC homology 1, basic leucine zipper transcription factor 1 b / BACH1* / O14867* / BTB domain and CNC homolog 1*ENSDARG0000000219612


Protein motifs (from Interpro)
Interpro ID Name
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029845  Nuclear factor erythroid 2-related factor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IGI
 biological_processGO:0071379 cellular response to prostaglandin stimulus IMP
 biological_processGO:0071466 cellular response to xenobiotic stimulus IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IPI
 molecular_functionGO:0003700 DNA-binding transcription factor activity IGI
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure glutathione disulfide increased amount , abnormal
anatomical structure glutathione decreased amount , abnormal
anatomical structure amount , ameliorated
anatomical structure increased amount , abnormal
Show

 ZFA:0000123 liver liver amount , ameliorated
liver increased amount , abnormal
Show

 ZFA:0000354 gill gill increased amount , abnormal
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 ZFA:0001094 whole organism whole organism amount , ameliorated
whole organism decreased life span , abnormal
whole organism dead , abnormal
whole organism increased amount , abnormal
Show

 ZFA:0001338 intestine intestine increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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