ENSDARG00000042970


Danio rerio

Features
Gene ID: ENSDARG00000042970
  
Biological name :gng8
  
Synonyms : gng8 / guanine nucleotide binding protein (G protein), gamma 8
  
Possible biological names infered from orthology : G protein subunit gamma 8 / P63078 / Q9UK08
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 25231160
Gene end: 25235926
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112923
Ensembl peptide - ENSDARP00000063088
NCBI entrez gene - 553609     See in Manteia.
RefSeq - NM_001177743
RefSeq Peptide - NP_001171214
swissprot - E9QCV9
swissprot - Q503Q6
ZFIN ID - ZDB-GENE-050522-312
Ensembl - ENSDARG00000042970
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GNG8ENSG00000167414Homo sapiens
 Gng8ENSMUSG00000063594Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gng2 / guanine nucleotide binding protein (G protein), gamma 2 / P59768* / P63213* / G protein subunit gamma 2*ENSDARG0000005683171
GNG4 / G protein subunit gamma 4 / P50150*ENSDARG0000011125966
gng3 / guanine nucleotide binding protein (G protein), gamma 3 / P63215* / P63216* / G protein subunit gamma 3*ENSDARG0000000955363
gng7 / guanine nucleotide binding protein (G protein), gamma 7 / O60262* / Q61016* / G protein subunit gamma 7*ENSDARG0000003869356
si:dkey-44g17.6 / GNG12* / Q9DAS9* / Q9UBI6* / G protein subunit gamma 12* / guanine nucleotide binding protein (G protein), gamma 12*ENSDARG0000009812353
gng12a / guanine nucleotide binding protein (G protein), gamma 12a / GNG12* / Q9UBI6* / Q9DAS9* / G protein subunit gamma 12* / guanine nucleotide binding protein (G protein), gamma 12*ENSDARG0000000337551
gng5 / guanine nucleotide binding protein (G protein), gamma 5 / P63218* / Q80SZ7* / G protein subunit gamma 5*ENSDARG0000003983046
gng10 / guanine nucleotide binding protein (G protein), gamma 10 / P50151* / G protein subunit gamma 10*ENSDARG0000010404341
si:dkey-204f11.64ENSDARG0000009469540
si:ch211-286b5.5ENSDARG0000009666139
GNG14 / si:dkey-117i10.1 / Gm5741* / A0A1W2PPG7* / G protein subunit gamma 14*ENSDARG0000006253739


Protein motifs (from Interpro)
Interpro ID Name
 IPR001770  G-protein, gamma subunit
 IPR015898  G-protein gamma-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
Activation of G protein gated Potassium channels
G-protein activation
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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