ENSDARG00000043250


Danio rerio

Features
Gene ID: ENSDARG00000043250
  
Biological name :ppm1ab
  
Synonyms : ppm1ab / protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
  
Possible biological names infered from orthology : P35813 / P49443 / PPM1A / protein phosphatase 1A, magnesium dependent, alpha isoform / protein phosphatase, Mg2+/Mn2+ dependent 1A
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 20600971
Gene end: 20611063
  
Corresponding Affymetrix probe sets: Dr.20992.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000146872
Ensembl peptide - ENSDARP00000063491
NCBI entrez gene - 30703     See in Manteia.
RefSeq - NM_001161332
RefSeq - XM_005160487
RefSeq Peptide - NP_001154804
swissprot - Q5TZI2
swissprot - A0JMI7
ZFIN ID - ZDB-GENE-991102-14
Ensembl - ENSDARG00000043250
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPM1AENSGALG00000011917Gallus gallus
 PPM1AENSG00000100614Homo sapiens
 Ppm1aENSMUSG00000021096Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppm1aa / protein phosphatase, Mg2+/Mn2+ dependent, 1Aa / PPM1A* / P49443* / P35813* / protein phosphatase, Mg2+/Mn2+ dependent 1A* / protein phosphatase 1A, magnesium dependent, alpha isoform*ENSDARG0000003215579
ppm1bb / protein phosphatase, Mg2+/Mn2+ dependent, 1Bb / PPM1B* / P36993* / O75688* / protein phosphatase, Mg2+/Mn2+ dependent 1B* / protein phosphatase 1B, magnesium dependent, beta isoform*ENSDARG0000001149667
ppm1ba / protein phosphatase, Mg2+/Mn2+ dependent, 1Ba / PPM1B* / P36993* / O75688* / protein phosphatase, Mg2+/Mn2+ dependent 1B* / protein phosphatase 1B, magnesium dependent, beta isoform*ENSDARG0000000188866
ppm1na / protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative) / PPM1N* / Q8BGL1* / Q8N819* / Probable protein phosphatase 1N * / protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)*ENSDARG0000001023149
ppm1nb / protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative) / PPM1N* / Q8BGL1* / Q8N819* / Probable protein phosphatase 1N * / protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)*ENSDARG0000005703248


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR012911  Protein serine/threonine phosphatase 2C, C-terminal
 IPR015655  Protein phosphatase 2C family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Energy dependent regulation of mTOR by LKB1-AMPK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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