ENSDARG00000043509


Danio rerio

Features
Gene ID: ENSDARG00000043509
  
Biological name :rpl11
  
Synonyms : ribosomal protein L11 / rpl11
  
Possible biological names infered from orthology : 60S ribosomal protein L11 / Gm10036 / Gm5093 / P62913 / Q9CXW4
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 43780970
Gene end: 43786940
  
Corresponding Affymetrix probe sets: Dr.1353.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000063869
NCBI entrez gene - 415229     See in Manteia.
swissprot - Q6IQI6
ZFIN ID - ZDB-GENE-040625-147
Ensembl - ENSDARG00000043509
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPL11ENSGALG00000030378Gallus gallus
 RPL11ENSG00000142676Homo sapiens
 Gm10036ENSMUSG00000058064Mus musculus
 Gm5093ENSMUSG00000091742Mus musculus
 Rpl11ENSMUSG00000059291Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002132  Ribosomal protein L5
 IPR020929  Ribosomal protein L5, conserved site
 IPR022803  Ribosomal protein L5 domain superfamily
 IPR031309  Ribosomal protein L5, C-terminal
 IPR031310  Ribosomal protein L5, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IBA
 biological_processGO:0006412 translation IBA
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030218 erythrocyte differentiation IMP
 biological_processGO:0042541 hemoglobin biosynthetic process IMP
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0048821 erythrocyte development IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IBA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain deformed , abnormal
brain apoptotic , abnormal
brain structure , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000029 hindbrain hindbrain malformed , abnormal
Show

 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm decreased amount , abnormal
intermediate cell mass of mesoderm cell proliferation decreased occurrence , abnormal
intermediate cell mass of mesoderm hematopoietic multipotent progenitor cell decreased amount , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure amount , ameliorated
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary aplastic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000076 swim bladder swim bladder absent , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
yolk edematous , abnormal
yolk quality , abnormal
Show

 ZFA:0000100 cerebellum cerebellum aplastic , abnormal
Show

 ZFA:0000106 extension extension decreased size , abnormal
extension decreased thickness , abnormal
extension morphology , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye increased amount , abnormal
Show

 ZFA:0000108 fin fin deformed , abnormal
Show

 ZFA:0000109 forebrain forebrain increased size , abnormal
forebrain protruding , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
fourth ventricle opaque , abnormal
Show

 ZFA:0000112 gut gut aplastic , abnormal
gut quality , abnormal
gut hypoplastic , abnormal
gut immature , abnormal
gut absent , abnormal
Show

 ZFA:0000114 heart heart edematous , exacerbated
heart edematous , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
liver immature , abnormal
liver absent , abnormal
Show

 ZFA:0000138 otic placode otic placode shape , abnormal
otic placode decreased size , abnormal
Show

 ZFA:0000186 common cardinal vein common cardinal vein circulating cell decreased amount , abnormal
Show

 ZFA:0000217 inner ear inner ear morphology , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000445 optic tectum optic tectum increased size , abnormal
optic tectum opaque , abnormal
Show

 ZFA:0000547 mouth mouth absent , abnormal
Show

 ZFA:0001058 caudal fin caudal fin shortened , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism dead , abnormal
whole organism viable , abnormal
whole organism decreased pigmentation , abnormal
whole organism polysome decreased amount , abnormal
whole organism increased amount , abnormal
whole organism decreased life span , abnormal
Show

 ZFA:0001114 head head opaque , abnormal
head decreased size , abnormal
head aplastic , abnormal
head apoptotic process increased occurrence , abnormal
head apoptotic process increased occurrence , exacerbated
head increased amount , abnormal
head aplastic , ameliorated
Show

 ZFA:0001115 trunk trunk bent , abnormal
Show

 ZFA:0001117 post-vent region post-vent region bent , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , exacerbated
Meckels cartilage malformed , exacerbated
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , exacerbated
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0001580 neurocranium neurocranium malformed , exacerbated
Show

 ZFA:0001617 otolith otolith deformed , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
nucleate erythrocyte increased size , abnormal
nucleate erythrocyte irregularly shaped , abnormal
Show

 ZFA:0009325 erythroid lineage cell erythroid lineage cell absent , abnormal
erythroid lineage cell increased size , abnormal
erythroid lineage cell decreased amount , ameliorated
erythroid lineage cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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