ENSDARG00000045516


Danio rerio

Features
Gene ID: ENSDARG00000045516
  
Biological name :itih2
  
Synonyms : inter-alpha-trypsin inhibitor heavy chain 2 / itih2
  
Possible biological names infered from orthology : P19823
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 25187912
Gene end: 25215968
  
Corresponding Affymetrix probe sets: Dr.852.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000066931
Ensembl peptide - ENSDARP00000066932
NCBI entrez gene - 406280     See in Manteia.
RefSeq - NM_001327825
RefSeq Peptide - NP_001314754
swissprot - Q5RH28
swissprot - Q5RH29
ZFIN ID - ZDB-GENE-040426-1942
Ensembl - ENSDARG00000045516
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ITIH2ENSGALG00000006833Gallus gallus
 ITIH2ENSG00000151655Homo sapiens
 Itih2ENSMUSG00000037254Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
itih1 / inter-alpha-trypsin inhibitor heavy chain 1 / ITIH3* / Q61704* / P19827* / Q06033* / Q61702* / inter-alpha-trypsin inhibitor heavy chain 3* / Inter-alpha-trypsin inhibitor heavy cha...ENSDARG0000005505335
itih3a / inter-alpha-trypsin inhibitor heavy chain 3a / ITIH1* / ITIH3* / Q61702* / Q61704* / P19827* / Q06033* / inter-alpha-trypsin inhibitor heavy chain 3* / inter-alpha-trypsin inhibito...ENSDARG0000005503635
itih5 / inter-alpha-trypsin inhibitor heavy chain family, member 5 / Q8BJD1* / Inter-alpha-trypsin inhibitor heavy chain H5 *ENSDARG0000004551730
itih3b / inter-alpha-trypsin inhibitor heavy chain 3b / ITIH4* / A6X935* / Q14624* / Inter alpha-trypsin inhibitor, heavy chain 4 * / inter-alpha-trypsin inhibitor heavy chain family member 4*ENSDARG0000010272227
zgc:112265 / ITIH4* / A6X935* / Q14624* / Inter alpha-trypsin inhibitor, heavy chain 4 * / inter-alpha-trypsin inhibitor heavy chain family member 4*ENSDARG0000010040626
itih6 / inter-alpha-trypsin inhibitor heavy chain family, member 6 / Q6UXX5*ENSDARG0000005603722


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR010600  Inter-alpha-trypsin inhibitor heavy chain, C-terminal
 IPR013694  VIT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030212 hyaluronan metabolic process IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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