ENSMUSG00000037254


Mus musculus

Features
Gene ID: ENSMUSG00000037254
  
Biological name :Itih2
  
Synonyms : inter-alpha trypsin inhibitor, heavy chain 2 / Itih2
  
Possible biological names infered from orthology : P19823
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A1
Gene start: 10094593
Gene end: 10131396
  
Corresponding Affymetrix probe sets: 10480003 (MoGene1.0st)   1417618_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124636
Ensembl peptide - ENSMUSP00000124880
Ensembl peptide - ENSMUSP00000046530
NCBI entrez gene - 16425     See in Manteia.
MGI - MGI:96619
RefSeq - NM_010582
RefSeq Peptide - NP_034712
swissprot - Q3UEG7
swissprot - E0CX69
swissprot - G3X977
Ensembl - ENSMUSG00000037254
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itih2ENSDARG00000045516Danio rerio
 ITIH2ENSGALG00000006833Gallus gallus
 ITIH2ENSG00000151655Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Itih3 / Q61704 / Inter-alpha-trypsin inhibitor heavy chain H3 / Q06033* / inter-alpha-trypsin inhibitor heavy chain 3*ENSMUSG0000000652238
Itih1 / Q61702 / Inter-alpha-trypsin inhibitor heavy chain H1 / P19827* / inter-alpha-trypsin inhibitor heavy chain 1*ENSMUSG0000000652937
Itih5 / Q8BJD1 / Inter-alpha-trypsin inhibitor heavy chain H5 / inter-alpha-trypsin inhibitor heavy chain family member 5*ENSMUSG0000002578031
Itih4 / A6X935 / Inter alpha-trypsin inhibitor, heavy chain 4 / Q14624* / inter-alpha-trypsin inhibitor heavy chain family member 4*ENSMUSG0000002192230


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR010600  Inter-alpha-trypsin inhibitor heavy chain, C-terminal
 IPR013694  VIT domain
 IPR036465  von Willebrand factor A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030212 hyaluronan metabolic process IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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