ENSDARG00000045658


Danio rerio

Features
Gene ID: ENSDARG00000045658
  
Biological name :msrb3
  
Synonyms : methionine sulfoxide reductase B3 / msrb3
  
Possible biological names infered from orthology : Q8IXL7
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 12890668
Gene end: 12914307
  
Corresponding Affymetrix probe sets: Dr.3730.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000067134
Ensembl peptide - ENSDARP00000120380
Ensembl peptide - ENSDARP00000122154
Ensembl peptide - ENSDARP00000123270
Ensembl peptide - ENSDARP00000155341
NCBI entrez gene - 415184     See in Manteia.
RefSeq - NM_001320378
RefSeq Peptide - NP_001307307
swissprot - F6P046
swissprot - Q5TZH6
swissprot - Q5TZH8
ZFIN ID - ZDB-GENE-040625-74
Ensembl - ENSDARG00000045658
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MSRB3ENSGALG00000026661Gallus gallus
 MSRB3ENSG00000174099Homo sapiens
 Msrb3ENSMUSG00000051236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
msrb2 / methionine sulfoxide reductase B2 / Q78J03* / Q9Y3D2* / Methionine-R-sulfoxide reductase B2, mitochondrial *ENSDARG0000001845931


Protein motifs (from Interpro)
Interpro ID Name
 IPR002579  Peptide methionine sulphoxide reductase MrsB
 IPR011057  Mss4-like superfamily
 IPR028427  Peptide methionine sulfoxide reductase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0030091 protein repair IEA
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
 molecular_functionGO:0033743 peptide-methionine (R)-S-oxide reductase activity IEA


Pathways (from Reactome)
Pathway description
Protein repair


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000217 inner ear inner ear decreased size , abnormal
inner ear stereocilium decreased length , abnormal
inner ear stereocilium decreased width , abnormal
Show

 ZFA:0000243 neuromast neuromast kinocilium decreased length , abnormal
neuromast decreased amount , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal malformed , abnormal
Show

 ZFA:0001617 otolith otolith amount , abnormal
otolith decreased size , abnormal
otolith mislocalised , abnormal
otolith fused with otolith , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell apoptotic process increased process quality , abnormal
neuromast hair cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000031435 zgc:56493 / TXN* / Txn1* / Q6A555* / Q86VQ3* / P10639* / Q69AB2* / TXNDC2* / TXNDC8* / P10599* / thioredoxin* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain contai...  / reaction
 ENSDARG00000044125 txn / thioredoxin / Txn1* / Q6A555* / Q86VQ3* / TXNDC8* / P10599* / P10639* / Q69AB2* / TXNDC2* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 8* / thio...  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr