ENSDARG00000045760


Danio rerio

Features
Gene ID: ENSDARG00000045760
  
Biological name :prmt8b
  
Synonyms : prmt8b / protein arginine methyltransferase 8b / Q5RGQ2
  
Possible biological names infered from orthology : PRMT8 / protein arginine methyltransferase 8 / protein arginine N-methyltransferase 8 / Q6PAK3 / Q9NR22
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 11144600
Gene end: 11165961
  
Corresponding Affymetrix probe sets: Dr.22371.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000059488
Ensembl peptide - ENSDARP00000148688
Ensembl peptide - ENSDARP00000153084
NCBI entrez gene - 564110     See in Manteia.
RefSeq - NM_001045042
RefSeq Peptide - NP_001038507
swissprot - Q5RGQ2
ZFIN ID - ZDB-GENE-030131-7791
Ensembl - ENSDARG00000045760
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRMT8ENSGALG00000013272Gallus gallus
 PRMT8ENSG00000111218Homo sapiens
 Prmt8ENSMUSG00000030350Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRMT8 / protein arginine methyltransferase 8 / Q9NR22*ENSDARG0000004063386
prmt1 / protein arginine methyltransferase 1 / Q99873* / Q9JIF0* / protein arginine N-methyltransferase 1*ENSDARG0000001024662
prmt3 / protein arginine methyltransferase 3 / O60678* / Q922H1* / protein arginine N-methyltransferase 3*ENSDARG0000001979138
prmt6 / protein arginine methyltransferase 6 / Q96LA8*ENSDARG0000006970630
carm1 / Q6DC04 / coactivator-associated arginine methyltransferase 1 / Q9WVG6* / Q86X55* / Histone-arginine methyltransferase CARM1 *ENSDARG0000001869829
carm1l / coactivator-associated arginine methyltransferase 1, likeENSDARG0000009153126
prmt2 / protein arginine methyltransferase 2 / P55345* / protein arginine N-methyltransferase 2*ENSDARG0000006321226


Protein motifs (from Interpro)
Interpro ID Name
 IPR025799  Protein arginine N-methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0018216 peptidyl-arginine methylation ISS
 biological_processGO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine IEA
 biological_processGO:0030917 midbrain-hindbrain boundary development IMP
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034969 histone arginine methylation IEA
 biological_processGO:0035247 peptidyl-arginine omega-N-methylation IEA
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0048813 dendrite morphogenesis IMP
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008469 histone-arginine N-methyltransferase activity IBA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity ISS
 molecular_functionGO:0016273 arginine N-methyltransferase activity IMP
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035241 protein-arginine omega-N monomethyltransferase activity ISS
 molecular_functionGO:0035242 protein-arginine omega-N asymmetric methyltransferase activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain malformed , abnormal
brain dorsal-ventral axis decreased length , abnormal
brain neuron disorganized , abnormal
brain neuron decreased amount , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary morphology , abnormal
midbrain hindbrain boundary edematous , abnormal
Show

 ZFA:0000075 spinal cord spinal cord neuron decreased amount , abnormal
Show

 ZFA:0000084 yolk yolk swollen , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000111 germ ring germ ring increased thickness , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000128 midbrain midbrain decreased size , abnormal
midbrain decreased width , abnormal
Show

 ZFA:0000135 notochord notochord increased width , abnormal
notochord shortened , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
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 ZFA:0009071 Purkinje cell Purkinje cell dendrite decreased branchiness , abnormal
Purkinje cell dendrite decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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