ENSG00000111218


Homo sapiens

Features
Gene ID: ENSG00000111218
  
Biological name :PRMT8
  
Synonyms : PRMT8 / protein arginine methyltransferase 8 / Q9NR22
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.32
Gene start: 3381349
Gene end: 3593973
  
Corresponding Affymetrix probe sets: 207772_s_at (Human Genome U133 Plus 2.0 Array)   230839_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000372067
Ensembl peptide - ENSP00000414507
NCBI entrez gene - 56341     See in Manteia.
OMIM - 610086
RefSeq - XM_017019645
RefSeq - NM_001256536
RefSeq - NM_019854
RefSeq - XM_017019644
RefSeq Peptide - NP_001243465
RefSeq Peptide - NP_062828
swissprot - Q9NR22
Ensembl - ENSG00000111218
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRMT8ENSDARG00000040633Danio rerio
 prmt8bENSDARG00000045760Danio rerio
 PRMT8ENSGALG00000013272Gallus gallus
 Prmt8ENSMUSG00000030350Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRMT1 / Q99873 / protein arginine methyltransferase 1ENSG0000012645773
PRMT3 / O60678 / protein arginine methyltransferase 3ENSG0000018523843
CARM1 / Q86X55 / coactivator associated arginine methyltransferase 1ENSG0000014245332
PRMT6 / Q96LA8 / protein arginine methyltransferase 6ENSG0000019889029
PRMT2 / P55345 / protein arginine methyltransferase 2ENSG0000016031028


Protein motifs (from Interpro)
Interpro ID Name
 IPR025799  Protein arginine N-methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0016571 histone methylation IDA
 biological_processGO:0018216 peptidyl-arginine methylation IDA
 biological_processGO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine IDA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034969 histone arginine methylation IEA
 biological_processGO:0043393 regulation of protein binding TAS
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008469 histone-arginine N-methyltransferase activity IDA
 molecular_functionGO:0008757 S-adenosylmethionine-dependent methyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035241 protein-arginine omega-N monomethyltransferase activity IDA
 molecular_functionGO:0035242 protein-arginine omega-N asymmetric methyltransferase activity IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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