ENSG00000185238


Homo sapiens

Features
Gene ID: ENSG00000185238
  
Biological name :PRMT3
  
Synonyms : O60678 / PRMT3 / protein arginine methyltransferase 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.1
Gene start: 20387530
Gene end: 20509294
  
Corresponding Affymetrix probe sets: 213320_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000329586
Ensembl peptide - ENSP00000435151
Ensembl peptide - ENSP00000434260
Ensembl peptide - ENSP00000397766
Ensembl peptide - ENSP00000331879
NCBI entrez gene - 10196     See in Manteia.
OMIM - 603190
RefSeq - XM_017017081
RefSeq - NM_001145166
RefSeq - NM_001145167
RefSeq - NM_005788
RefSeq - XM_011519836
RefSeq Peptide - NP_001138639
RefSeq Peptide - NP_005779
RefSeq Peptide - NP_001138638
swissprot - O60678
swissprot - A0A0A0MSN7
swissprot - E9PRB4
swissprot - E9PLF6
Ensembl - ENSG00000185238
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prmt3ENSDARG00000019791Danio rerio
 PRMT3ENSGALG00000003958Gallus gallus
 Prmt3ENSMUSG00000030505Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRMT1 / Q99873 / protein arginine methyltransferase 1ENSG0000012645732
PRMT8 / Q9NR22 / protein arginine methyltransferase 8ENSG0000011121832
CARM1 / Q86X55 / coactivator associated arginine methyltransferase 1ENSG0000014245326
PRMT2 / P55345 / protein arginine methyltransferase 2ENSG0000016031025
PRMT6 / Q96LA8 / protein arginine methyltransferase 6ENSG0000019889021


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR025799  Protein arginine N-methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IDA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034969 histone arginine methylation IEA
 biological_processGO:0035246 peptidyl-arginine N-methylation IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008469 histone-arginine N-methyltransferase activity IBA
 molecular_functionGO:0016274 protein-arginine N-methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0035242 protein-arginine omega-N asymmetric methyltransferase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
Protein methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000140988 RPS2 / P15880 / ribosomal protein S2  / reaction






 

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