ENSDARG00000045946


Danio rerio

Features
Gene ID: ENSDARG00000045946
  
Biological name :sec24d
  
Synonyms : sec24d / SEC24 homolog D, COPII coat complex component
  
Possible biological names infered from orthology : O94855 / Sec24 related gene family, member D (S. cerevisiae)
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 69905307
Gene end: 69951096
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000035564
NCBI entrez gene - 553407     See in Manteia.
swissprot - F1QRB4
ZFIN ID - ZDB-GENE-070117-2501
Ensembl - ENSDARG00000045946
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SEC24DENSGALG00000011998Gallus gallus
 O94855ENSG00000150961Homo sapiens
 Sec24dENSMUSG00000039234Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sec24c / SEC24 homolog C, COPII coat complex component / P53992* / Sec24 related gene family, member C (S. cerevisiae)*ENSDARG0000010351658
sec24b / SEC24 homolog B, COPII coat complex component / O95487* / Sec24 related gene family, member B (S. cerevisiae)*ENSDARG0000007190626
sec24a / SEC24 homolog A, COPII coat complex component / O95486*ENSDARG0000010437523
si:dkey-13n15.2ENSDARG0000006180611


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR006895  Zinc finger, Sec23/Sec24-type
 IPR006896  Sec23/Sec24, trunk domain
 IPR006900  Sec23/Sec24, helical domain
 IPR007123  Gelsolin-like domain
 IPR012990  Sec23/Sec24 beta-sandwich
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0060536 cartilage morphogenesis IMP
 biological_processGO:0070278 extracellular matrix constituent secretion IMP
 cellular_componentGO:0030127 COPII vesicle coat IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000257 pectoral fin cartilage pectoral fin cartilage malformed , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
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 ZFA:0000292 surface structure surface structure quality , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal aplastic , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001114 head head decreased length , abnormal
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 ZFA:0001161 pectoral fin pectoral fin quality , abnormal
pectoral fin kinked , abnormal
pectoral fin decreased length , abnormal
pectoral fin degenerate , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased length , abnormal
Meckels cartilage cell-cell adherens junction increased amount , abnormal
Meckels cartilage chondrocyte length , abnormal
Meckels cartilage chondrocyte disorganized , abnormal
Meckels cartilage chondrocyte obtuse , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
ceratohyal cartilage chondrocyte obtuse , abnormal
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 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage physical object quality , abnormal
pharyngeal arch cartilage chondrocyte malformed , abnormal
pharyngeal arch cartilage chondrocyte disorganized , abnormal
pharyngeal arch cartilage decreased size , abnormal
pharyngeal arch cartilage extracellular matrix decreased volume , abnormal
pharyngeal arch cartilage immature , abnormal
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 ZFA:0001500 auditory capsule auditory capsule malformed , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage decreased size , abnormal
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 ZFA:0009084 chondrocyte chondrocyte malformed , abnormal
chondrocyte actin filament disorganized , abnormal
chondrocyte cell-cell adherens junction increased amount , abnormal
chondrocyte undifferentiated , abnormal
chondrocyte endoplasmic reticulum lumen swollen , abnormal
chondrocyte Golgi apparatus decreased size , abnormal
chondrocyte Golgi apparatus disorganized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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