ENSDARG00000104375


Danio rerio

Features
Gene ID: ENSDARG00000104375
  
Biological name :sec24a
  
Synonyms : sec24a / SEC24 homolog A, COPII coat complex component
  
Possible biological names infered from orthology : O95486 / Protein transport protein Sec24A / Q3U2P1
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 45685757
Gene end: 45709267
  
Corresponding Affymetrix probe sets: Dr.14350.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000130391
NCBI entrez gene - 100000526     See in Manteia.
swissprot - A0A0R4ICL5
ZFIN ID - ZDB-GENE-120926-1
Ensembl - ENSDARG00000104375
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SEC24AENSGALG00000006417Gallus gallus
 O95486ENSG00000113615Homo sapiens
 Q3U2P1ENSMUSG00000036391Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sec24b / SEC24 homolog B, COPII coat complex component / O95487* / Sec24 related gene family, member B (S. cerevisiae)*ENSDARG0000007190652
sec24c / SEC24 homolog C, COPII coat complex component / P53992* / Sec24 related gene family, member C (S. cerevisiae)*ENSDARG0000010351623
sec24d / SEC24 homolog D, COPII coat complex component / O94855*ENSDARG0000004594622
si:dkey-13n15.2ENSDARG000000618066


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR006895  Zinc finger, Sec23/Sec24-type
 IPR006896  Sec23/Sec24, trunk domain
 IPR006900  Sec23/Sec24, helical domain
 IPR007123  Gelsolin-like domain
 IPR012990  Sec23/Sec24 beta-sandwich
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0030127 COPII vesicle coat IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002949 ppp6c / protein phosphatase 6, catalytic subunit / O00743* / Q9CQR6* / Serine/threonine-protein phosphatase 6 catalytic subunit *  / reaction
 ENSDARG00000019581 uso1 / USO1 vesicle transport factor / O60763* / Q9Z1Z0* / USO1 vesicle docking factor*  / reaction / complex
 ENSDARG00000006125 Q6P3K7 / csnk1db / casein kinase 1, delta b / Q9DC28* / CSNK1D* / P48730* / casein kinase 1 delta*  / reaction
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / reaction / complex
 ENSDARG00000008370 Q7T2E3 / csnk1da / casein kinase 1, delta a / CSNK1D* / P48730* / casein kinase 1 delta*  / reaction
 ENSDARG00000029663 rab1ab / RAB1A, member RAS oncogene family b / Rab1* / RAB1A* / P62821* / P62820* / Ras-related protein Rab-1A * / RAB1A, member RAS oncogene family*  / reaction / complex
 ENSDARG00000054807 sec13 / SEC13 homolog, nuclear pore and COPII coat complex component / P55735* / Q9D1M0*  / complex / reaction
 ENSDARG00000021082 sec31a / SEC31 homolog A, COPII coat complex component / O94979* / Q3UPL0* / Protein transport protein Sec31A *  / complex / reaction
 ENSDARG00000100435 Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b / SEC22B* / O08547* / O75396* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/p...  / reaction / complex
 ENSDARG00000104230 Q7SZE5 / sec23a / Sec23 homolog A, COPII coat complex component / Q15436* / Q01405* / Protein transport protein Sec23A * / Sec23 homolog A, coat complex II component*  / reaction / complex
 ENSDARG00000099554 sec16b / SEC16 homolog B, endoplasmic reticulum export factor / Q91XT4* / Q96JE7* / Protein transport protein Sec16B *  / complex
 ENSDARG00000015887 b2ml / beta-2-microglobulin, like / B2M* / P01887* / P61769* / beta-2-microglobulin*  / complex
 ENSDARG00000053136 b2m / Q04475 / beta-2-microglobulin / P01887* / P61769*  / complex
 ENSDARG00000103403 sar1b / secretion associated, Ras related GTPase 1B / Q9Y6B6*  / complex / reaction
 ENSDARG00000071168 zmp:0000001138 / B2M* / P61769* / beta-2-microglobulin*  / complex
 ENSDARG00000063197 golga2 / golgin A2 / A6NMD2* / A7E2F4* / A8MQT2* / A8MZA4* / D6RF30* / F8WBI6* / A6NCC3* / A6NDK9* / A6NDN3* / H3BSY2* / I6L899* / P0CG33* / P0CJ92* / Q08379* / Q08AF8* / Q8N9W4* / Q921M4* ...  / reaction / complex
 ENSDARG00000003641 tfg / trk-fused gene / Q92734*  / complex






 

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