ENSDARG00000053136


Danio rerio

Features
Gene ID: ENSDARG00000053136
  
Biological name :b2m
  
Synonyms : b2m / beta-2-microglobulin / Q04475
  
Possible biological names infered from orthology : P01887 / P61769
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 12785964
Gene end: 12795489
  
Corresponding Affymetrix probe sets: Dr.184.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000148267
Ensembl peptide - ENSDARP00000148347
Ensembl peptide - ENSDARP00000069612
Ensembl peptide - ENSDARP00000110049
Ensembl peptide - ENSDARP00000125475
NCBI entrez gene - 30400     See in Manteia.
RefSeq - NM_131163
RefSeq Peptide - NP_001153240
RefSeq Peptide - NP_571238
swissprot - B0UYS1
swissprot - Q04475
swissprot - H0WF44
ZFIN ID - ZDB-GENE-980526-88
Ensembl - ENSDARG00000053136
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B2MENSGALG00000002160Gallus gallus
 B2MENSG00000166710Homo sapiens
 B2mENSMUSG00000060802Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
b2ml / beta-2-microglobulin, like / B2M* / P01887* / P61769* / beta-2-microglobulin*ENSDARG0000001588759
zmp:0000001138 / B2M* / P61769* / beta-2-microglobulin*ENSDARG0000007116835


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR000719  Protein kinase domain
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011029  Death-like domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR015707  Beta-2-Microglobulin
 IPR033610  Interleukin-1 receptor-associated kinase 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002474 antigen processing and presentation of peptide antigen via MHC class I IEA
 biological_processGO:0006955 immune response IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0042612 MHC class I protein complex IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000054807 sec13 / SEC13 homolog, nuclear pore and COPII coat complex component / P55735* / Q9D1M0*  / complex / reaction
 ENSDARG00000021082 sec31a / SEC31 homolog A, COPII coat complex component / O94979* / Q3UPL0* / Protein transport protein Sec31A *  / complex / reaction
 ENSDARG00000071906 sec24b / SEC24 homolog B, COPII coat complex component / O95487* / Sec24 related gene family, member B (S. cerevisiae)*  / complex
 ENSDARG00000103516 sec24c / SEC24 homolog C, COPII coat complex component / P53992* / Sec24 related gene family, member C (S. cerevisiae)*  / complex
 ENSDARG00000104230 Q7SZE5 / sec23a / Sec23 homolog A, COPII coat complex component / Q15436* / Q01405* / Protein transport protein Sec23A * / Sec23 homolog A, coat complex II component*  / complex
 ENSDARG00000104375 sec24a / SEC24 homolog A, COPII coat complex component / O95486*  / complex
 ENSDARG00000103403 sar1b / secretion associated, Ras related GTPase 1B / Q9Y6B6*  / complex
 ENSDARG00000102640 pdia3 / protein disulfide isomerase family A, member 3 / P27773* / P30101* / Protein disulfide-isomerase A3 *  / complex






 

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