ENSDARG00000102640


Danio rerio

Features
Gene ID: ENSDARG00000102640
  
Biological name :pdia3
  
Synonyms : pdia3 / protein disulfide isomerase family A, member 3
  
Possible biological names infered from orthology : P27773 / P30101 / Protein disulfide-isomerase A3
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 30343012
Gene end: 30357027
  
Corresponding Affymetrix probe sets: Dr.6501.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131695
Ensembl peptide - ENSDARP00000134643
swissprot - A0A0R4IBZ3
swissprot - A0A0R4IGN3
ZFIN ID - ZDB-GENE-031002-9
Ensembl - ENSDARG00000102640
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDIA3ENSGALG00000008348Gallus gallus
 PDIA3ENSG00000167004Homo sapiens
 Pdia3ENSMUSG00000027248Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zgc:77086ENSDARG0000001401563
zgc:100906ENSDARG0000003359961
pdia4 / protein disulfide isomerase family A, member 4 / P13667*ENSDARG0000001849143
p4hb / prolyl 4-hydroxylase, beta polypeptide / P07237* / P09103* / prolyl 4-hydroxylase subunit beta*ENSDARG0000010511633
pdia2 / protein disulfide isomerase family A, member 2 / D3Z6P0* / Q13087* / Protein disulfide-isomerase A2 *ENSDARG0000001826331
zgc:136472 / PDILT* / Q9DAN1* / Q8N807* / protein disulfide isomerase like, testis expressed* / Protein disulfide-isomerase-like protein of the testis *ENSDARG0000005844523
erp44 / endoplasmic reticulum protein 44 / Q9BS26* / Q9D1Q6* / Endoplasmic reticulum resident protein 44 *ENSDARG0000001900817
tmx3a / thioredoxin related transmembrane protein 3a / TMX3* / Q8BXZ1* / Q96JJ7* / Protein disulfide-isomerase TMX3 * / thioredoxin related transmembrane protein 3*ENSDARG0000003889415
tmx3b / thioredoxin related transmembrane protein 3b / TMX3* / Q96JJ7* / thioredoxin related transmembrane protein 3*ENSDARG000000884666


Protein motifs (from Interpro)
Interpro ID Name
 IPR005788  Disulphide isomerase
 IPR005792  Protein disulphide isomerase
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045454 cell redox homeostasis IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0003756 protein disulfide isomerase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
Calnexin/calreticulin cycle
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037488 canx / calnexin / P27824* / P35564*  / complex / reaction
 ENSDARG00000076290 calr / calreticulin / P14211* / P27797*  / reaction / complex
 ENSDARG00000071168 zmp:0000001138 / B2M* / P61769* / beta-2-microglobulin*  / complex
 ENSDARG00000053136 b2m / Q04475 / beta-2-microglobulin / P01887* / P61769*  / complex
 ENSDARG00000015887 b2ml / beta-2-microglobulin, like / B2M* / P01887* / P61769* / beta-2-microglobulin*  / complex






 

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