ENSGALG00000008348


Gallus gallus

Features
Gene ID: ENSGALG00000008348
  
Biological name :PDIA3
  
Synonyms : PDIA3 / Protein disulfide-isomerase A3 / Q8JG64
  
Possible biological names infered from orthology : P27773 / P30101 / protein disulfide isomerase family A member 3
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 20161520
Gene end: 20170430
  
Corresponding Affymetrix probe sets: Gga.3802.1.S1_s_at (Chicken Array)   Gga.3802.2.S1_a_at (Chicken Array)   GgaAffx.22540.1.A1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000013574
NCBI entrez gene - 373899     See in Manteia.
RefSeq - NM_204110
RefSeq Peptide - NP_989441
swissprot - Q8JG64
Ensembl - ENSGALG00000008348
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdia3ENSDARG00000102640Danio rerio
 PDIA3ENSG00000167004Homo sapiens
 Pdia3ENSMUSG00000027248Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDIA4 / protein disulfide-isomerase A4 / P13667* / protein disulfide isomerase family A member 4*ENSGALG0000004300639
P4HB / protein disulfide-isomerase precursor / P09103* / P07237* / prolyl 4-hydroxylase subunit beta* / prolyl 4-hydroxylase, beta polypeptide*ENSGALG0000003829032
PDIA2 / protein disulfide isomerase family A member 2 / D3Z6P0* / Q13087* / Protein disulfide-isomerase A2 *ENSGALG0000004007027
PDILT / protein disulfide isomerase like, testis expressed / Q8N807* / Q9DAN1* / Protein disulfide-isomerase-like protein of the testis *ENSGALG0000000200624
ERP44 / endoplasmic reticulum protein 44 / Q9BS26* / Q9D1Q6* / Endoplasmic reticulum resident protein 44 *ENSGALG0000001345217
TMX3 / Gallus gallus thioredoxin related transmembrane protein 3 (TMX3), transcript variant 1, mRNA. / Q8BXZ1* / Q96JJ7* / Protein disulfide-isomerase TMX3 * / thioredoxin related transmemb...ENSGALG0000001375715
ERP27* / Q96DN0* / Q9D8U3* / endoplasmic reticulum protein 27* / Endoplasmic reticulum resident protein 27 *ENSGALG0000001173910


Protein motifs (from Interpro)
Interpro ID Name
 IPR005788  Disulphide isomerase
 IPR005792  Protein disulphide isomerase
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0003756 protein disulfide isomerase activity IBA
 molecular_functionGO:0015037 peptide disulfide oxidoreductase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Calnexin/calreticulin cycle
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000032148 CANX / calnexin / P27824* / P35564*  / complex / reaction
 ENSGALG00000002160 B2M / P21611 / Beta-2-microglobulin / P01887* / P61769*  / complex






 

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