ENSDARG00000037488


Danio rerio

Features
Gene ID: ENSDARG00000037488
  
Biological name :canx
  
Synonyms : calnexin / canx
  
Possible biological names infered from orthology : P27824 / P35564
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 16432738
Gene end: 16476863
  
Corresponding Affymetrix probe sets: Dr.6391.1.S1_at (Zebrafish Array)   NM_213448_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000083454
NCBI entrez gene - 406757     See in Manteia.
RefSeq - NM_213448
RefSeq - XM_009307813
RefSeq Peptide - NP_998613
swissprot - F1QKS4
ZFIN ID - ZDB-GENE-040426-2797
Ensembl - ENSDARG00000037488
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CANXENSGALG00000032148Gallus gallus
 CANXENSG00000127022Homo sapiens
 CanxENSMUSG00000020368Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
clgn / calmegin / O14967* / P52194* / Mus musculus calmegin (Clgn), transcript variant 2, mRNA.*ENSDARG0000000931559
si:ch211-274f20.2ENSDARG0000005857931
calr3b / calreticulin 3bENSDARG0000010280828
calr3a / calreticulin 3aENSDARG0000010397927
calr / calreticulin / P14211* / P27797*ENSDARG0000007629027


Protein motifs (from Interpro)
Interpro ID Name
 IPR001580  Calreticulin/calnexin
 IPR009033  Calreticulin/calnexin, P domain superfamily
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018124  Calreticulin/calnexin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0048916 posterior lateral line development IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
Calnexin/calreticulin cycle
Interleukin-27 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000243 neuromast neuromast decreased amount , abnormal
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 ZFA:0001157 posterior lateral line primordium posterior lateral line primordium neuromast decreased amount , abnormal
posterior lateral line primordium apoptotic process increased occurrence , abnormal
posterior lateral line primordium cell proliferation decreased occurrence , abnormal
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 ZFA:0009367 neuromast hair cell neuromast hair cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / reaction / complex
 ENSDARG00000102640 pdia3 / protein disulfide isomerase family A, member 3 / P27773* / P30101* / Protein disulfide-isomerase A3 *  / reaction / complex
 ENSDARG00000076290 calr / calreticulin / P14211* / P27797*  / complex






 

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