ENSDARG00000103403


Danio rerio

Features
Gene ID: ENSDARG00000103403
  
Biological name :sar1b
  
Synonyms : sar1b / secretion associated, Ras related GTPase 1B
  
Possible biological names infered from orthology : Q9CQC9 / Q9Y6B6
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 45673433
Gene end: 45685063
  
Corresponding Affymetrix probe sets: Dr.10893.1.A1_at (Zebrafish Array)   NM_001024377_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000136017
NCBI entrez gene - 554177     See in Manteia.
RefSeq - NM_001024377
RefSeq Peptide - NP_001019548
swissprot - Q6PBX2
ZFIN ID - ZDB-GENE-040426-1958
Ensembl - ENSDARG00000103403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SAR1BENSGALG00000038753Gallus gallus
 SAR1BENSG00000152700Homo sapiens
 Sar1bENSMUSG00000020386Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sar1ab / secretion associated, Ras related GTPase 1Ab / SAR1A* / Q9NR31* / secretion associated Ras related GTPase 1A*ENSDARG0000003332087


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006687  Small GTPase superfamily, SAR1-type
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030299 intestinal cholesterol absorption IMP
 biological_processGO:0035265 organ growth IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Chylomicron assembly
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000123 liver liver decreased size , abnormal
liver organ growth decreased process quality , abnormal
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 ZFA:0000140 pancreas pancreas decreased size , abnormal
pancreas organ growth decreased process quality , abnormal
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 ZFA:0000445 optic tectum optic tectum white matter position , abnormal
optic tectum white matter decreased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001114 head head anterior-posterior axis decreased length , abnormal
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 ZFA:0001161 pectoral fin pectoral fin kinked , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
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 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
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 ZFA:0001440 rhombic lip rhombic lip white matter position , abnormal
rhombic lip white matter decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000009087 cd74a / CD74 molecule, major histocompatibility complex, class II invariant chain a / CD74* / P04233* / P04441* / CD74 molecule* / CD74 antigen (invariant polypeptide of major histocompatib...  / reaction / complex
 ENSDARG00000054807 sec13 / SEC13 homolog, nuclear pore and COPII coat complex component / P55735* / Q9D1M0*  / complex / reaction
 ENSDARG00000021082 sec31a / SEC31 homolog A, COPII coat complex component / O94979* / Q3UPL0* / Protein transport protein Sec31A *  / complex / reaction
 ENSDARG00000071906 sec24b / SEC24 homolog B, COPII coat complex component / O95487* / Sec24 related gene family, member B (S. cerevisiae)*  / complex / reaction
 ENSDARG00000103516 sec24c / SEC24 homolog C, COPII coat complex component / P53992* / Sec24 related gene family, member C (S. cerevisiae)*  / complex / reaction
 ENSDARG00000100435 Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b / SEC22B* / O08547* / O75396* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/p...  / reaction / complex
 ENSDARG00000104230 Q7SZE5 / sec23a / Sec23 homolog A, COPII coat complex component / Q15436* / Q01405* / Protein transport protein Sec23A * / Sec23 homolog A, coat complex II component*  / reaction / complex
 ENSDARG00000099554 sec16b / SEC16 homolog B, endoplasmic reticulum export factor / Q91XT4* / Q96JE7* / Protein transport protein Sec16B *  / complex
 ENSDARG00000104375 sec24a / SEC24 homolog A, COPII coat complex component / O95486*  / complex / reaction
 ENSDARG00000003641 tfg / trk-fused gene / Q92734*  / complex
 ENSDARG00000053136 b2m / Q04475 / beta-2-microglobulin / P01887* / P61769*  / complex
 ENSDARG00000071168 zmp:0000001138 / B2M* / P61769* / beta-2-microglobulin*  / complex
 ENSDARG00000015887 b2ml / beta-2-microglobulin, like / B2M* / P01887* / P61769* / beta-2-microglobulin*  / complex
 ENSDARG00000101602 preb / prolactin regulatory element binding / Q9HCU5* / Q9WUQ2*  / reaction






 

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