ENSDARG00000052121


Danio rerio

Features
Gene ID: ENSDARG00000052121
  
Biological name :rag2
  
Synonyms : rag2 / recombination activating gene 2
  
Possible biological names infered from orthology : P21784 / P55895 / recombination activating 2
  
Species: Danio rerio
  
Chr. number: 25
Strand: -1
Band:
Gene start: 9010425
Gene end: 9013963
  
Corresponding Affymetrix probe sets: Dr.5743.1.S1_at (Zebrafish Array)   NM_131385_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000068402
NCBI entrez gene - 30658     See in Manteia.
RefSeq - NM_131385
RefSeq Peptide - NP_571460
swissprot - Q1RLW7
ZFIN ID - ZDB-GENE-990415-235
Ensembl - ENSDARG00000052121
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAG2ENSGALG00000046408Gallus gallus
 RAG2ENSG00000175097Homo sapiens
 Rag2ENSMUSG00000032864Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004321  V-D-J recombination activating protein 2
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011043  Galactose oxidase/kelch, beta-propeller
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015915  Kelch-type beta propeller
 IPR025162  Recombination activating protein 2, PHD domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006310 DNA recombination IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000669 head kidney head kidney lymphocyte decreased amount , abnormal
head kidney T cell decreased amount , abnormal
head kidney mature B cell decreased amount , abnormal
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 ZFA:0001078 thymus thymus morphology , abnormal
thymus has fewer parts of type T cell , abnormal
thymus has extra parts of type fat cell , abnormal
thymus decreased size , abnormal
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 ZFA:0001094 whole organism whole organism neoplastic , abnormal
whole organism melanoma increased occurrence , abnormal
whole organism neuroblastoma increased occurrence , abnormal
whole organism Lymphoid neoplasms increased occurrence , abnormal
whole organism embryonal rhabdomyosarcoma increased occurrence , abnormal
whole organism sterile , abnormal
whole organism decreased life span , abnormal
Show

 ZFA:0005779 thymic epithelium thymic epithelium has fewer parts of type epithelial cell , abnormal
Show

 ZFA:0009250 lymphocyte lymphocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr