ENSDARG00000052866


Danio rerio

Features
Gene ID: ENSDARG00000052866
  
Biological name :htt
  
Synonyms : htt / huntingtin
  
Possible biological names infered from orthology : P42858
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 41293964
Gene end: 41374117
  
Corresponding Affymetrix probe sets: Dr.586.1.S1_at (Zebrafish Array)   NM_131018_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000069263
NCBI entrez gene - 30214     See in Manteia.
RefSeq - NM_131018
RefSeq - XM_005160016
RefSeq Peptide - NP_571093
swissprot - B7ZDE9
ZFIN ID - ZDB-GENE-990415-131
Ensembl - ENSDARG00000052866
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HTTENSGALG00000015635Gallus gallus
 HTTENSG00000197386Homo sapiens
 HttENSMUSG00000029104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000091  Huntingtin
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024613  Huntingtin, middle-repeat
 IPR028426  Huntingtin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001841 neural tube formation IMP
 biological_processGO:0006879 cellular iron ion homeostasis IMP
 biological_processGO:0021954 central nervous system neuron development IMP
 biological_processGO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0048884 neuromast development IMP
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0071698 olfactory placode development IMP
 biological_processGO:0090017 anterior neural plate formation IMP
 biological_processGO:2000047 regulation of cell-cell adhesion mediated by cadherin IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0008134 transcription factor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood low saturation , abnormal
Show

 ZFA:0000008 brain brain necrotic , abnormal
brain apoptotic , abnormal
Show

 ZFA:0000048 olfactory placode olfactory placode composition , abnormal
olfactory placode olfactory receptor cell absent , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000076 swim bladder swim bladder aplastic , abnormal
Show

 ZFA:0000077 tail bud tail bud decreased size , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton has fewer parts of type pharyngeal arch cartilage , abnormal
Show

 ZFA:0000106 extension extension decreased size , abnormal
extension aplastic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II aplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism increased curvature , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head neuroblast dispersed , abnormal
Show

 ZFA:0001115 trunk trunk larval melanophore stripe misaligned with whole organism anterior-posterior axis, abnormal
trunk melanocyte disorganized , abnormal
Show

 ZFA:0001117 post-vent region post-vent region morphology , abnormal
post-vent region curved dorsal , abnormal
post-vent region curvature , abnormal
Show

 ZFA:0001135 neural tube neural tube shape , abnormal
neural tube neuroepithelial cell disorganized , abnormal
neural tube disorganized , abnormal
Show

 ZFA:0001261 ventricular system ventricular system decreased size , abnormal
ventricular system increased size , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage curved caudal , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage morphology , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage morphology , abnormal
pharyngeal arch cartilage aplastic , abnormal
Show

 ZFA:0001469 lateral line lateral line neuromast decreased amount , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage morphology , abnormal
ceratobranchial cartilage aplastic , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 decreased size , abnormal
pharyngeal arch 2 mislocalised ventrally , abnormal
pharyngeal arch 2 disoriented , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 decreased size , abnormal
pharyngeal arch 1 mislocalised ventrally , abnormal
pharyngeal arch 1 disoriented , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 aplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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