ENSDARG00000053215


Danio rerio

Features
Gene ID: ENSDARG00000053215
  
Biological name :me1
  
Synonyms : malic enzyme 1, NADP(+)-dependent, cytosolic / me1
  
Possible biological names infered from orthology : malic enzyme 1 / NADP-dependent malic enzyme / P06801 / P48163
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 32832213
Gene end: 33001153
  
Corresponding Affymetrix probe sets: Dr.23977.1.A1_at (Zebrafish Array)   Dr.23977.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000143251
Ensembl peptide - ENSDARP00000092744
Ensembl peptide - ENSDARP00000113885
NCBI entrez gene - 768196     See in Manteia.
RefSeq - NM_001310037
RefSeq - XM_005158369
RefSeq - XM_017351366
RefSeq Peptide - NP_001296966
swissprot - F1QU54
swissprot - A0A286Y7Z2
swissprot - F1QAX1
ZFIN ID - ZDB-GENE-061013-438
Ensembl - ENSDARG00000053215
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ME1ENSGALG00000015849Gallus gallus
 ME1ENSG00000065833Homo sapiens
 Me1ENSMUSG00000032418Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
me3 / malic enzyme 3, NADP(+)-dependent, mitochondrial / Q16798* / Q8BMF3* / malic enzyme 3* / NADP-dependent malic enzyme, mitochondrial *ENSDARG0000000230573
me2 / malic enzyme 2, NAD(+)-dependent, mitochondrial / P23368* / Q99KE1* / malic enzyme 2* / NAD-dependent malic enzyme, mitochondrial *ENSDARG0000010071855


Protein motifs (from Interpro)
Interpro ID Name
 IPR001891  Malic oxidoreductase
 IPR012301  Malic enzyme, N-terminal domain
 IPR012302  Malic enzyme, NAD-binding
 IPR015884  Malic enzyme, conserved site
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006090 pyruvate metabolic process IBA
 biological_processGO:0006108 malate metabolic process IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 molecular_functionGO:0004470 malic enzyme activity IEA
 molecular_functionGO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEA
 molecular_functionGO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Pyruvate metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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