ENSDARG00000053912


Danio rerio

Features
Gene ID: ENSDARG00000053912
  
Biological name :fbl
  
Synonyms : fbl / fibrillarin
  
Possible biological names infered from orthology : A6NHQ2 / FBLL1 / fibrillarin like 1 / P22087 / P35550 / Q80WS3 / rRNA 2-O-methyltransferase fibrillarin / rRNA/tRNA 2-O-methyltransferase fibrillarin-like protein 1
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 42177659
Gene end: 42186093
  
Corresponding Affymetrix probe sets: Dr.3347.1.S1_at (Zebrafish Array)   NM_213002_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000070509
NCBI entrez gene - 406275     See in Manteia.
RefSeq - NM_213002
RefSeq Peptide - NP_998167
swissprot - Q7ZTZ4
ZFIN ID - ZDB-GENE-040426-1936
Ensembl - ENSDARG00000053912
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FBLENSG00000105202Homo sapiens
 FBLL1ENSG00000188573Homo sapiens
 FblENSMUSG00000046865Mus musculus
 Fbll1ENSMUSG00000051062Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000692  Fibrillarin
 IPR020813  Fibrillarin, conserved site
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000494 box C/D snoRNA 3"-end processing IBA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0031167 rRNA methylation IBA
 biological_processGO:1990258 histone glutamine methylation IBA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0015030 Cajal body IBA
 cellular_componentGO:0031428 box C/D snoRNP complex IBA
 cellular_componentGO:0032040 small-subunit processome IBA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008649 rRNA methyltransferase activity IBA
 molecular_functionGO:1990259 histone-glutamine methyltransferase activity IBA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000029 hindbrain hindbrain quality , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary quality , abnormal
midbrain hindbrain boundary condensed , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle distended , abnormal
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 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
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 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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