ENSG00000105202


Homo sapiens

Features
Gene ID: ENSG00000105202
  
Biological name :FBL
  
Synonyms : FBL / fibrillarin / P22087
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 39834458
Gene end: 39846414
  
Corresponding Affymetrix probe sets: 211623_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472805
Ensembl peptide - ENSP00000472433
Ensembl peptide - ENSP00000472726
Ensembl peptide - ENSP00000221801
Ensembl peptide - ENSP00000469072
Ensembl peptide - ENSP00000469249
Ensembl peptide - ENSP00000471350
Ensembl peptide - ENSP00000471867
Ensembl peptide - ENSP00000472419
NCBI entrez gene - 2091     See in Manteia.
OMIM - 134795
RefSeq - XM_011526623
RefSeq - NM_001436
RefSeq - XM_005258651
RefSeq Peptide - NP_001427
swissprot - M0R299
swissprot - M0R2B0
swissprot - M0R2Q4
swissprot - M0R2U2
swissprot - M0QXC9
swissprot - P22087
swissprot - M0QXL5
swissprot - M0R1H0
swissprot - M0R0P1
Ensembl - ENSG00000105202
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fblENSDARG00000053912Danio rerio
 FblENSMUSG00000046865Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FBLL1 / A6NHQ2 / fibrillarin like 1ENSG0000018857375


Protein motifs (from Interpro)
Interpro ID Name
 IPR000692  Fibrillarin
 IPR020813  Fibrillarin, conserved site
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000494 box C/D snoRNA 3"-end processing IBA
 biological_processGO:0001649 osteoblast differentiation HDA
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0016074 snoRNA metabolic process IEA
 biological_processGO:0031167 rRNA methylation IBA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0048254 snoRNA localization IMP
 biological_processGO:1990258 histone glutamine methylation IDA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0001651 dense fibrillar component IEA
 cellular_componentGO:0001652 granular component IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031428 box C/D snoRNP complex NAS
 cellular_componentGO:0032040 small-subunit processome IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001094 TFIID-class transcription factor binding IPI
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008649 rRNA methyltransferase activity IBA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0051117 ATPase binding IPI
 molecular_functionGO:1990259 histone-glutamine methyltransferase activity IDA


Pathways (from Reactome)
Pathway description
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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