ENSDARG00000054208


Danio rerio

Features
Gene ID: ENSDARG00000054208
  
Biological name :phkg2
  
Synonyms : phkg2 / phosphorylase kinase, gamma 2 (testis)
  
Possible biological names infered from orthology : P15735 / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform / phosphorylase kinase catalytic subunit gamma 2 / Q9DB30
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 28888975
Gene end: 28901184
  
Corresponding Affymetrix probe sets: Dr.14244.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000070836
NCBI entrez gene - 393937     See in Manteia.
RefSeq - NM_200962
RefSeq - XM_009306599
RefSeq Peptide - NP_957256
swissprot - F1QXS6
ZFIN ID - ZDB-GENE-040426-825
Ensembl - ENSDARG00000054208
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PHKG2ENSG00000156873Homo sapiens
 Phkg2ENSMUSG00000030815Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
phkg1b / phosphorylase kinase, gamma 1b (muscle) / PHKG1* / Q16816* / P07934* / phosphorylase kinase catalytic subunit gamma 1* / Phosphorylase b kinase gamma catalytic chain, skeletal musc...ENSDARG0000006949866
phkg1a / phosphorylase kinase, gamma 1a (muscle) / PHKG1* / Q16816* / P07934* / phosphorylase kinase catalytic subunit gamma 1* / Phosphorylase b kinase gamma catalytic chain, skeletal musc...ENSDARG0000003060465
dclk2a / doublecortin-like kinase 2a / DCLK2* / Q6PGN3* / Q8N568* / doublecortin like kinase 2* / Serine/threonine-protein kinase DCLK2 *ENSDARG0000003409330
dclk1b / doublecortin-like kinase 1b / DCLK1* / O15075* / Q9JLM8* / doublecortin like kinase 1* / Mus musculus doublecortin-like kinase 1 (Dclk1), transcript variant 12, mRNA.*ENSDARG0000010466430
dclk1a / doublecortin-like kinase 1a / DCLK1* / O15075* / Q9JLM8* / doublecortin like kinase 1* / Mus musculus doublecortin-like kinase 1 (Dclk1), transcript variant 12, mRNA.*ENSDARG0000001885629
stk33 / serine/threonine kinase 33 / Q924X7* / Q9BYT3* / Serine/threonine-protein kinase 33 *ENSDARG0000005431827
dclk3 / doublecortin-like kinase 3 / Q8BWQ5* / Q9C098* / Serine/threonine-protein kinase DCLK3 *ENSDARG0000007899725
dclk2b / doublecortin-like kinase 2bENSDARG000001028452


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR002291  Phosphorylase kinase, gamma catalytic subunit
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR020636  Calcium/calmodulin-dependent/calcium-dependent protein kinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005977 glycogen metabolic process IBA
 biological_processGO:0005978 glycogen biosynthetic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005964 phosphorylase kinase complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004689 phosphorylase kinase activity IBA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Glycogen breakdown (glycogenolysis)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002197 pygl / phosphorylase, glycogen, liver / P06737* / Q9ET01* / glycogen phosphorylase L* / Glycogen phosphorylase, liver form *  / reaction
 ENSDARG00000054208 phkg2 / phosphorylase kinase, gamma 2 (testis) / Q9DB30* / P15735* / phosphorylase kinase catalytic subunit gamma 2* / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform *  / complex
 ENSDARG00000030687 phka2 / phosphorylase kinase, alpha 2 (liver) / Q8BWJ3* / P46019* / phosphorylase kinase regulatory subunit alpha 2* / Phosphorylase b kinase regulatory subunit alpha, liver isoform *  / complex
 ENSDARG00000078284 phkb / phosphorylase kinase, beta / Q7TSH2* / Q93100* / phosphorylase kinase regulatory subunit beta* / Phosphorylase b kinase regulatory subunit beta *  / complex
 ENSDARG00000100825 calm2a / calm2b / calm3a / Q6PI52 / calmodulin 2a (phosphorylase kinase, delta)  / complex






 

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