ENSDARG00000054337


Danio rerio

Features
Gene ID: ENSDARG00000054337
  
Biological name :ap1g2
  
Synonyms : adaptor-related protein complex 1, gamma 2 subunit / ap1g2
  
Possible biological names infered from orthology : AP-1 complex subunit gamma-like 2 / O75843 / O88512
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 38287358
Gene end: 38312757
  
Corresponding Affymetrix probe sets: Dr.5071.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000134266
NCBI entrez gene - 100007877     See in Manteia.
swissprot - B0R024
ZFIN ID - ZDB-GENE-030616-587
Ensembl - ENSDARG00000054337
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AP1G2ENSG00000213983Homo sapiens
 Ap1g2ENSMUSG00000040701Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ap1g1 / adaptor-related protein complex 1, gamma 1 subunit / O43747* / P22892* / AP-1 complex subunit gamma-1 *ENSDARG0000010239461
ap4e1 / adaptor-related protein complex 4, epsilon 1 subunit / Q80V94* / Q9UPM8* / AP-4 complex subunit epsilon-1 *ENSDARG0000010368422


Protein motifs (from Interpro)
Interpro ID Name
 IPR002553  Clathrin/coatomer adaptor, adaptin-like, N-terminal
 IPR008152  Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
 IPR008153  Gamma-adaptin ear (GAE) domain
 IPR011989  Armadillo-like helical
 IPR013041  Clathrin adaptor, appendage, Ig-like subdomain superfamily
 IPR016024  Armadillo-type fold
 IPR017107  Adaptor protein complex AP-1, gamma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0003401 axis elongation IMP
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030121 AP-1 adaptor complex IEA
 cellular_componentGO:0030131 clathrin adaptor complex IEA


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000005 artery artery malformed , abnormal
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 ZFA:0000029 hindbrain hindbrain morphology , abnormal
hindbrain decreased amount , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased amount , abnormal
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 ZFA:0000075 spinal cord spinal cord neuron decreased amount , abnormal
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 ZFA:0000079 telencephalon telencephalon decreased amount , abnormal
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 ZFA:0000082 vein vein malformed , abnormal
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 ZFA:0000101 diencephalon diencephalon decreased amount , abnormal
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 ZFA:0000109 forebrain forebrain morphology , abnormal
forebrain decreased amount , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle absent , abnormal
fourth ventricle decreased amount , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000128 midbrain midbrain morphology , abnormal
midbrain decreased amount , abnormal
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 ZFA:0000135 notochord notochord axis elongation decreased occurrence , abnormal
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 ZFA:0000155 somite somite shape , abnormal
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 ZFA:0000160 tegmentum tegmentum decreased amount , abnormal
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 ZFA:0001058 caudal fin caudal fin curved , abnormal
caudal fin kinked , abnormal
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 ZFA:0001069 ventral fin fold ventral fin fold absent , abnormal
ventral fin fold decreased size , abnormal
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 ZFA:0001094 whole organism whole organism decreased life span , abnormal
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 ZFA:0001114 head head morphology , abnormal
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 ZFA:0001115 trunk trunk decreased amount , abnormal
trunk decreased thickness , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel malformed , abnormal
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 ZFA:0009044 blood cell blood cell mislocalised , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020960 hgs / hepatocyte growth factor-regulated tyrosine kinase substrate / O14964* / hepatocyte growth factor-regulated tyrosine kinase substrate isoform 2 *  / reaction / complex






 

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