ENSDARG00000054799


Danio rerio

Features
Gene ID: ENSDARG00000054799
  
Biological name :rfc1
  
Synonyms : replication factor C (activator 1) 1 / rfc1 / rpl9
  
Possible biological names infered from orthology : P35251 / replication factor C subunit 1
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 23243093
Gene end: 23274038
  
Corresponding Affymetrix probe sets: Dr.1202.3.S1_at (Zebrafish Array)   Dr.17100.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113369
Ensembl peptide - ENSDARP00000119715
Ensembl peptide - ENSDARP00000156035
NCBI entrez gene - 100037336     See in Manteia.
NCBI entrez gene - 336702     See in Manteia.
RefSeq - NM_001089491
RefSeq Peptide - NP_001082960
swissprot - E9QDP5
swissprot - F1Q5P6
ZFIN ID - ZDB-GENE-030131-8646
ZFIN ID - ZDB-GENE-070410-99
Ensembl - ENSDARG00000054799
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RFC1ENSGALG00000014298Gallus gallus
 RFC1ENSG00000035928Homo sapiens
 Rfc1ENSMUSG00000029191Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000702  Ribosomal protein L6
 IPR001357  BRCT domain
 IPR002359  Ribosomal protein L6, conserved site-2
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR008921  DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
 IPR012178  Replication factor C subunit 1
 IPR013725  DNA replication factor RFC1, C-terminal
 IPR020040  Ribosomal protein L6, alpha-beta domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005663 DNA replication factor C complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003689 DNA clamp loader activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary condensed , abnormal
midbrain hindbrain boundary quality , abnormal
Show

 ZFA:0000076 swim bladder swim bladder quality , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
Show

 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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