ENSDARG00000055639


Danio rerio

Features
Gene ID: ENSDARG00000055639
  
Biological name :ruvbl2
  
Synonyms : P83571 / ruvbl2 / RuvB-like AAA ATPase 2
  
Possible biological names infered from orthology : Q9WTM5 / Q9Y230 / RuvB-like protein 2
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 30759232
Gene end: 30770807
  
Corresponding Affymetrix probe sets: Dr.24909.1.S1_at (Zebrafish Array)   NM_174860_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072482
NCBI entrez gene - 317678     See in Manteia.
RefSeq - NM_174860
RefSeq Peptide - NP_777285
swissprot - P83571
ZFIN ID - ZDB-GENE-030109-1
Ensembl - ENSDARG00000055639
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9Y230ENSG00000183207Homo sapiens
 Q9WTM5ENSMUSG00000003868Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR010339  TIP49, C-terminal
 IPR027238  RuvB-like
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000492 box C/D snoRNP assembly IBA
 biological_processGO:0003351 epithelial cilium movement IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006338 chromatin remodeling IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0016573 histone acetylation IBA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0044458 motile cilium assembly IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0048565 digestive tract development IMP
 biological_processGO:0060420 regulation of heart growth IMP
 biological_processGO:0070286 axonemal dynein complex assembly IMP
 cellular_componentGO:0000812 Swr1 complex IBA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0031011 Ino80 complex IBA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IBA
 cellular_componentGO:0071339 MLL1 complex ISS
 cellular_componentGO:0097255 R2TP complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003678 DNA helicase activity ISS
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0043141 ATP-dependent 5"-3" DNA helicase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
brain cellular response to DNA damage stimulus increased occurrence , abnormal
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle hypertrophic , abnormal
cardiac ventricle hyperplastic , abnormal
cardiac ventricle non-functional , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct increased diameter , abnormal
pronephric duct motile cilium has fewer parts of type pronephric duct inner dynein arm, abnormal
pronephric duct motile cilium has fewer parts of type pronephric duct outer dynein arm, abnormal
Show

 ZFA:0000151 pronephros pronephros quality , abnormal
pronephros cystic , abnormal
Show

 ZFA:0000152 retina retina morphology , abnormal
Show

 ZFA:0000529 kidney kidney cystic , abnormal
Show

 ZFA:0001094 whole organism whole organism bent , abnormal
whole organism curved ventral , abnormal
whole organism necrotic , abnormal
whole organism absent , abnormal
whole organism decreased amount , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk curved ventral , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton decreased size , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased size , abnormal
Show

 ZFA:0001623 posterior pronephric duct posterior pronephric duct motile cilium immobile , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell increased amount , abnormal
cardiac muscle cell sarcomere increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr