ENSDARG00000056138


Danio rerio

Features
Gene ID: ENSDARG00000056138
  
Biological name :sf3b1
  
Synonyms : sf3b1 / splicing factor 3b, subunit 1
  
Possible biological names infered from orthology : O75533
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 32161623
Gene end: 32177117
  
Corresponding Affymetrix probe sets: Dr.7117.1.A1_at (Zebrafish Array)   Dr.7117.2.S1_at (Zebrafish Array)   XM_679219_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000073029
NCBI entrez gene - 446117     See in Manteia.
RefSeq - XM_679219
swissprot - F1QQZ1
ZFIN ID - ZDB-GENE-040827-3
Ensembl - ENSDARG00000056138
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SF3B1ENSGALG00000008038Gallus gallus
 SF3B1ENSG00000115524Homo sapiens
 Sf3b1ENSMUSG00000025982Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR015016  Splicing factor 3B subunit 1
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000245 spliceosomal complex assembly IBA
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0042981 regulation of apoptotic process IGI
 biological_processGO:0060216 definitive hemopoiesis IMP
 biological_processGO:0060218 hematopoietic stem cell differentiation IMP
 biological_processGO:0061515 myeloid cell development IMP
 cellular_componentGO:0005686 U2 snRNP IBA
 cellular_componentGO:0005689 U12-type spliceosomal complex IBA
 cellular_componentGO:0071004 U2-type prespliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IBA
 molecular_functionGO:0003729 mRNA binding IBA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000045 neural crest neural crest apoptotic , abnormal
Show

 ZFA:0000084 yolk yolk quality , abnormal
yolk circular , abnormal
yolk grey , abnormal
Show

 ZFA:0000094 blood island blood island myeloid cell decreased amount , abnormal
Show

 ZFA:0000106 extension extension decreased thickness , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000295 trigeminal ganglion trigeminal ganglion disorganized , abnormal
trigeminal ganglion neuron decreased amount , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism necrotic , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk atrophied , abnormal
Show

 ZFA:0001117 post-vent region post-vent region bent , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch morphology , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0005237 erythroblast erythroblast increased amount , abnormal
Show

 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0009091 melanocyte melanocyte absent , abnormal
Show

 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

 ZFA:0009324 myeloid cell myeloid cell decreased amount , abnormal
Show

 ZFA:0009325 erythroid lineage cell erythroid lineage cell increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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