ENSDARG00000058022


Danio rerio

Features
Gene ID: ENSDARG00000058022
  
Biological name :ormdl2
  
Synonyms : ormdl2 / ORMDL sphingolipid biosynthesis regulator 2
  
Possible biological names infered from orthology : Mus musculus ORM1-like 2 (S. cerevisiae) (Ormdl2), transcript variant 4, mRNA. / Q53FV1 / Q9CQZ0
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 31962383
Gene end: 31969786
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000120650
Ensembl peptide - ENSDARP00000147132
NCBI entrez gene - 677753     See in Manteia.
RefSeq - NM_001040048
RefSeq Peptide - NP_001035137
swissprot - Q24JV2
ZFIN ID - ZDB-GENE-060331-113
Ensembl - ENSDARG00000058022
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ORMDL2ENSG00000123353Homo sapiens
 Ormdl2ENSMUSG00000025353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ormdl1 / Q8JFB7 / ORMDL sphingolipid biosynthesis regulator 1 / Q921I0* / Q9P0S3* / Gm28778* / ORM1-like protein 1 *ENSDARG0000001433382
Q5XJR6 / ormdl3 / ORMDL sphingolipid biosynthesis regulator 3 / Q8N138* / Q9CPZ6* / ORM1-like protein 3 *ENSDARG0000002555582


Protein motifs (from Interpro)
Interpro ID Name
 IPR007203  ORMDL family
 IPR029886  ORM1-like protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006672 ceramide metabolic process IEA
 biological_processGO:0090155 negative regulation of sphingolipid biosynthetic process IEA
 biological_processGO:0090156 cellular sphingolipid homeostasis IBA
 biological_processGO:1900060 negative regulation of ceramide biosynthetic process IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035339 SPOTS complex IBA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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