ENSG00000123353


Homo sapiens

Features
Gene ID: ENSG00000123353
  
Biological name :ORMDL2
  
Synonyms : ORMDL2 / ORMDL sphingolipid biosynthesis regulator 2 / Q53FV1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.2
Gene start: 55817919
Gene end: 55821879
  
Corresponding Affymetrix probe sets: 218556_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448788
Ensembl peptide - ENSP00000449461
Ensembl peptide - ENSP00000243045
Ensembl peptide - ENSP00000447834
NCBI entrez gene - 29095     See in Manteia.
OMIM - 610074
RefSeq - NM_014182
RefSeq Peptide - NP_054901
swissprot - F8VWV8
swissprot - F8VXD5
swissprot - Q53FV1
Ensembl - ENSG00000123353
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ormdl2ENSDARG00000058022Danio rerio
 Ormdl2ENSMUSG00000025353Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ORMDL1 / Q9P0S3 / ORMDL sphingolipid biosynthesis regulator 1ENSG0000012869983
ORMDL3 / Q8N138 / ORMDL sphingolipid biosynthesis regulator 3ENSG0000017205780


Protein motifs (from Interpro)
Interpro ID Name
 IPR007203  ORMDL family
 IPR029886  ORM1-like protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006672 ceramide metabolic process IMP
 biological_processGO:0090155 negative regulation of sphingolipid biosynthetic process IEA
 biological_processGO:0090156 cellular sphingolipid homeostasis IBA
 biological_processGO:1900060 negative regulation of ceramide biosynthetic process IMP
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035339 SPOTS complex IBA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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