ENSMUSG00000025353


Mus musculus

Features
Gene ID: ENSMUSG00000025353
  
Biological name :Ormdl2
  
Synonyms : Mus musculus ORM1-like 2 (S. cerevisiae) (Ormdl2), transcript variant 4, mRNA. / Ormdl2 / Q9CQZ0
  
Possible biological names infered from orthology : ORMDL sphingolipid biosynthesis regulator 2 / Q53FV1
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 128817902
Gene end: 128821645
  
Corresponding Affymetrix probe sets: 10373577 (MoGene1.0st)   1424235_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026409
Ensembl peptide - ENSMUSP00000151335
Ensembl peptide - ENSMUSP00000151644
Ensembl peptide - ENSMUSP00000151697
NCBI entrez gene - 66844     See in Manteia.
MGI - MGI:1914094
RefSeq - XM_006513959
RefSeq - NM_001359169
RefSeq - NM_001359170
RefSeq - NM_001359171
RefSeq - NM_024180
RefSeq Peptide - NP_001346099
RefSeq Peptide - NP_001346100
RefSeq Peptide - NP_077142
RefSeq Peptide - NP_001346098
swissprot - Q9CQZ0
Ensembl - ENSMUSG00000025353
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ormdl2ENSDARG00000058022Danio rerio
 ORMDL2ENSG00000123353Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ormdl1 / Q921I0 / ORM1-like protein 1 ENSMUSG0000002609782
Ormdl3 / Q9CPZ6 / ORM1-like protein 3 / Q8N138* / ORMDL sphingolipid biosynthesis regulator 3*ENSMUSG0000003815082
Gm28778 / ORMDL1* / Q9P0S3* / ORMDL sphingolipid biosynthesis regulator 1*ENSMUSG0000010067963


Protein motifs (from Interpro)
Interpro ID Name
 IPR007203  ORMDL family
 IPR029886  ORM1-like protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006672 ceramide metabolic process ISS
 biological_processGO:0090155 negative regulation of sphingolipid biosynthetic process IEA
 biological_processGO:0090156 cellular sphingolipid homeostasis IBA
 biological_processGO:1900060 negative regulation of ceramide biosynthetic process ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035339 SPOTS complex IBA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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