ENSG00000128699


Homo sapiens

Features
Gene ID: ENSG00000128699
  
Biological name :ORMDL1
  
Synonyms : ORMDL1 / ORMDL sphingolipid biosynthesis regulator 1 / Q9P0S3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q32.2
Gene start: 189770323
Gene end: 189784371
  
Corresponding Affymetrix probe sets: 223187_s_at (Human Genome U133 Plus 2.0 Array)   227548_at (Human Genome U133 Plus 2.0 Array)   228801_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402074
Ensembl peptide - ENSP00000386253
Ensembl peptide - ENSP00000407234
Ensembl peptide - ENSP00000326869
Ensembl peptide - ENSP00000376160
Ensembl peptide - ENSP00000376161
NCBI entrez gene - 94101     See in Manteia.
OMIM - 610073
RefSeq - XM_017005348
RefSeq - NM_016467
RefSeq - XM_005246970
RefSeq - XM_011512199
RefSeq - XM_011512200
RefSeq - XM_017005347
RefSeq - NM_001128150
RefSeq Peptide - NP_001121622
RefSeq Peptide - NP_057551
swissprot - F6WST4
swissprot - Q9P0S3
swissprot - A0A1B0GXE7
Ensembl - ENSG00000128699
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ormdl1ENSDARG00000014333Danio rerio
 ORMDL1ENSGALG00000036257Gallus gallus
 Gm28778ENSMUSG00000100679Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ORMDL3 / Q8N138 / ORMDL sphingolipid biosynthesis regulator 3ENSG0000017205784
ORMDL2 / Q53FV1 / ORMDL sphingolipid biosynthesis regulator 2ENSG0000012335383


Protein motifs (from Interpro)
Interpro ID Name
 IPR007203  ORMDL family
 IPR029884  ORM1-like protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006672 ceramide metabolic process IEA
 biological_processGO:0090155 negative regulation of sphingolipid biosynthetic process IEA
 biological_processGO:0090156 cellular sphingolipid homeostasis IBA
 biological_processGO:1900060 negative regulation of ceramide biosynthetic process IMP
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035339 SPOTS complex IBA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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