ENSDARG00000058451


Danio rerio

Features
Gene ID: ENSDARG00000058451
  
Biological name :rpl6
  
Synonyms : ribosomal protein L6 / rpl6
  
Possible biological names infered from orthology : P47911 / Q02878
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 2493794
Gene end: 2506384
  
Corresponding Affymetrix probe sets: Dr.284.3.S1_a_at (Zebrafish Array)   NM_001003844_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000136100
Ensembl peptide - ENSDARP00000091899
Ensembl peptide - ENSDARP00000107457
NCBI entrez gene - 336727     See in Manteia.
RefSeq - NM_001003844
RefSeq - NM_001328586
RefSeq Peptide - NP_001003844
RefSeq Peptide - NP_001315515
swissprot - Q567N5
swissprot - A0A0R4ILG7
ZFIN ID - ZDB-GENE-030131-8671
Ensembl - ENSDARG00000058451
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPL6ENSGALG00000004818Gallus gallus
 RPL6ENSG00000089009Homo sapiens
 Rpl6ENSMUSG00000029614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000915  60S ribosomal protein L6E
 IPR005568  Ribosomal protein L6, N-terminal
 IPR008991  Translation protein SH3-like domain superfamily
 IPR014722  Ribosomal protein L2, domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IBA
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0043009 chordate embryonic development IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IBA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003735 structural constituent of ribosome IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball increased size , abnormal
Show

 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000029 hindbrain hindbrain undulate , abnormal
hindbrain quality , abnormal
Show

 ZFA:0000035 lens lens decreased size , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary aplastic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
yolk quality , abnormal
Show

 ZFA:0000100 cerebellum cerebellum decreased thickness , abnormal
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 ZFA:0000106 extension extension decreased length , abnormal
extension decreased thickness , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000108 fin fin aplastic , abnormal
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 ZFA:0000109 forebrain forebrain increased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
fourth ventricle opaque , abnormal
fourth ventricle distended , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
Show

 ZFA:0000135 notochord notochord undulate , abnormal
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 ZFA:0000138 otic placode otic placode decreased size , abnormal
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 ZFA:0000140 pancreas pancreas decreased volume , abnormal
pancreas hypoplastic , abnormal
Show

 ZFA:0000152 retina retina decreased size , abnormal
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 ZFA:0000445 optic tectum optic tectum increased size , abnormal
optic tectum opaque , abnormal
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 ZFA:0001094 whole organism whole organism shape , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head circular , abnormal
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 ZFA:0001115 trunk trunk bent , abnormal
trunk decreased thickness , abnormal
Show

 ZFA:0001117 post-vent region post-vent region bent , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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