ENSDARG00000058819


Danio rerio

Features
Gene ID: ENSDARG00000058819
  
Biological name :nog1
  
Synonyms : nog1 / noggin 1
  
Possible biological names infered from orthology : NOG / noggin / P97466 / Q13253
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 10310090
Gene end: 10312232
  
Corresponding Affymetrix probe sets: Dr.8120.1.S1_at (Zebrafish Array)   NM_130983_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000076205
NCBI entrez gene - 30174     See in Manteia.
RefSeq - NM_130983
RefSeq Peptide - NP_571058
swissprot - Q6NV45
ZFIN ID - ZDB-GENE-991206-8
Ensembl - ENSDARG00000058819
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NOGENSGALG00000003114Gallus gallus
 NOGENSG00000183691Homo sapiens
 NogENSMUSG00000048616Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nog3 / noggin 3 / NOG* / noggin* / P97466* / Q13253*ENSDARG0000005352863
nog2 / Q9W740 / noggin 2ENSDARG0000004306644


Protein motifs (from Interpro)
Interpro ID Name
 IPR008717  Noggin
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IEA
 biological_processGO:0045596 negative regulation of cell differentiation IEA
 biological_processGO:0051216 cartilage development IEA
 cellular_componentGO:0005576 extracellular region IEA


Pathways (from Reactome)
Pathway description
Signaling by BMP


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased thickness , abnormal
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 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle mislocalised medially , abnormal
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 ZFA:0000079 telencephalon telencephalon protruding , abnormal
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 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton aplastic , abnormal
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 ZFA:0000100 cerebellum cerebellum decreased size , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000132 neural plate neural plate decreased length , abnormal
neural plate decreased thickness , abnormal
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 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
whole organism wholly dorsalized , ameliorated
whole organism cytolysis increased occurrence , abnormal
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 ZFA:0001114 head head agenesis , abnormal
head decreased size , abnormal
head anterior region truncated , abnormal
head anterior region agenesis , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000041430 bmp2b / bone morphogenetic protein 2b / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*  / reaction / complex






 

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