ENSDARG00000058848


Danio rerio

Features
Gene ID: ENSDARG00000058848
  
Biological name :mcoln1b
  
Synonyms : mcoln1b / mucolipin 1b
  
Possible biological names infered from orthology : MCOLN1 / mucolipin 1 / Q99J21 / Q9GZU1
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 5991765
Gene end: 6035766
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000076235
NCBI entrez gene - 795916     See in Manteia.
swissprot - E7FBN6
swissprot - K9JZV9
ZFIN ID - ZDB-GENE-130514-1
Ensembl - ENSDARG00000058848
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCOLN1ENSG00000090674Homo sapiens
 Mcoln1ENSMUSG00000004567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mcoln1a / mucolipin 1a / Q9GZU1* / MCOLN1* / Q99J21* / mucolipin 1*ENSDARG0000000228569
LO017850.1 / MCOLN3* / Q8TDD5* / mucolipin 3*ENSDARG0000010205045
mcoln3a / mucolipin 3a / Q8TDD5* / MCOLN3* / Q8R4F0* / mucolipin 3*ENSDARG0000007836345
mcoln2 / mucolipin 2 / Q8IZK6*ENSDARG0000009891832


Protein motifs (from Interpro)
Interpro ID Name
 IPR013122  Polycystin cation channel, PKD1/PKD2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
TRP channels
Transferrin endocytosis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic process increased occurrence , abnormal
Show

 ZFA:0000107 eye eye apoptotic process increased occurrence , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer cell decreased amount , abnormal
Show

 ZFA:0000152 retina retina apoptotic process increased occurrence , abnormal
retina apoptotic body increased amount , abnormal
Show

 ZFA:0000243 neuromast neuromast disorganized , abnormal
neuromast neuromast hair cell position , abnormal
Show

 ZFA:0000640 cornea cornea glycosaminoglycan increased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased life span , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer decreased thickness , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle increased amount , abnormal
skeletal muscle autophagy disrupted , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell increased amount , abnormal
skeletal muscle cell mitochondrion morphology , abnormal
skeletal muscle cell lysosome increased size , abnormal
skeletal muscle cell autophagosome increased amount , abnormal
skeletal muscle cell autophagosome aggregated , abnormal
skeletal muscle cell microtubule shortened , abnormal
skeletal muscle cell microtubule cytoskeleton disorganized , abnormal
skeletal muscle cell neuromuscular junction morphology , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell decreased amount , abnormal
neuromast hair cell nucleus irregularly shaped , abnormal
neuromast hair cell mitochondrion broken , abnormal
neuromast hair cell vacuole increased amount , abnormal
neuromast hair cell autophagy disrupted , abnormal
neuromast hair cell autolysosome increased amount , abnormal
neuromast hair cell kinocilium decreased length , abnormal
neuromast hair cell kinocilium decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr