ENSDARG00000062206


Danio rerio

Features
Gene ID: ENSDARG00000062206
  
Biological name :skiv2l
  
Synonyms : SKI2 homolog, superkiller viralicidic activity 2-like / skiv2l
  
Possible biological names infered from orthology : Q15477 / Ski2 like RNA helicase / superkiller viralicidic activity 2-like (S. cerevisiae)
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 26869428
Gene end: 26923957
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000084042
Ensembl peptide - ENSDARP00000146737
NCBI entrez gene - 559653     See in Manteia.
RefSeq - XM_005170047
swissprot - F1R881
ZFIN ID - ZDB-GENE-010430-5
Ensembl - ENSDARG00000062206
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q15477ENSG00000204351Homo sapiens
 Skiv2lENSMUSG00000040356Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mtrex / Mtr4 exosome RNA helicase / P42285* / Q9CZU3* / Skiv2l2* / Superkiller viralicidic activity 2-like 2 *ENSDARG0000001345729


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR012961  ATP-dependent RNA helicase Ski2, C-terminal
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016438  ATP-dependent RNA helicase Ski2-like
 IPR025696  rRNA-processing arch domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006401 RNA catabolic process IEA
 biological_processGO:0070478 nuclear-transcribed mRNA catabolic process, 3"-5" exonucleolytic nonsense-mediated decay IBA
 cellular_componentGO:0055087 Ski complex IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003724 RNA helicase activity IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000036778 hbs1l / HBS1-like translational GTPase / Q69ZS7* / Q9Y450* / HBS1-like protein *  / complex






 

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contact: otassy@igbmc.fr