ENSDARG00000062390


Danio rerio

Features
Gene ID: ENSDARG00000062390
  
Biological name :cdc42ep5
  
Synonyms : CDC42 effector protein (Rho GTPase binding) 5 / cdc42ep5
  
Possible biological names infered from orthology : 1700027J19Rik / CDC42 effector protein 5 / Q6NZY7 / Q9Z0X0
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 13875867
Gene end: 13881156
  
Corresponding Affymetrix probe sets: Dr.19864.1.S1_at (Zebrafish Array)   Dr.19864.2.S1_a_at (Zebrafish Array)   NM_001045846_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000084654
Ensembl peptide - ENSDARP00000120063
Ensembl peptide - ENSDARP00000117192
NCBI entrez gene - 558275     See in Manteia.
RefSeq - NM_001045846
RefSeq Peptide - NP_001039311
RefSeq Peptide - NP_001313306
swissprot - E9QCJ9
swissprot - F1R2T1
swissprot - E9QFE5
ZFIN ID - ZDB-GENE-030131-5813
Ensembl - ENSDARG00000062390
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6NZY7ENSG00000167617Homo sapiens
 Q9Z0X0ENSMUSG00000063838Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdc42ep4a / CDC42 effector protein (Rho GTPase binding) 4a / Q9H3Q1* / Q9JM96* / CDC42EP4* / CDC42 effector protein 4*ENSDARG0000010145722
cdc42ep4b / CDC42 effector protein (Rho GTPase binding) 4b / Q9H3Q1* / Q9JM96* / CDC42EP4* / CDC42 effector protein 4*ENSDARG0000004503622
cdc42ep1b / CDC42 effector protein (Rho GTPase binding) 1b / Q00587* / CDC42EP1* / CDC42 effector protein 1*ENSDARG0000007779221
cdc42ep1a / CDC42 effector protein (Rho GTPase binding) 1a / Q00587* / CDC42EP1* / CDC42 effector protein 1*ENSDARG0000007954920


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007266 Rho protein signal transduction IBA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0030838 positive regulation of actin filament polymerization IBA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017049 GTP-Rho binding IBA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032103 mapk6 / mitogen-activated protein kinase 6 / Q16659* / Q61532*  / reaction
 ENSDARG00000028082 mapkapk5 / mitogen-activated protein kinase-activated protein kinase 5 / Q8IW41*  / reaction






 

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