ENSG00000167617


Homo sapiens

Features
Gene ID: ENSG00000167617
  
Biological name :CDC42EP5
  
Synonyms : CDC42 effector protein 5 / CDC42EP5 / Q6NZY7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.42
Gene start: 54465026
Gene end: 54473264
  
Corresponding Affymetrix probe sets: 227850_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000301200
NCBI entrez gene - 148170     See in Manteia.
OMIM - 609171
RefSeq - NM_145057
RefSeq Peptide - NP_659494
swissprot - Q6NZY7
Ensembl - ENSG00000167617
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc42ep5ENSDARG00000062390Danio rerio
 Q9Z0X0ENSMUSG00000063838Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q00587 / CDC42EP1 / CDC42 effector protein 1ENSG0000012828343
Q9H3Q1 / CDC42EP4 / CDC42 effector protein 4ENSG0000017960441


Protein motifs (from Interpro)
Interpro ID Name
 IPR000095  CRIB domain
 IPR029273  Cdc42 effector


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007254 JNK cascade IEA
 biological_processGO:0007266 Rho protein signal transduction IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IDA
 biological_processGO:0031274 positive regulation of pseudopodium assembly IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017049 GTP-Rho binding IPI


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069956 MAPK6 / Q16659 / mitogen-activated protein kinase 6  / reaction
 ENSG00000122545 SEPT7 / Q16181 / septin 7  / reaction
 ENSG00000089022 Q8IW41 / MAPKAPK5 / mitogen-activated protein kinase-activated protein kinase 5  / reaction






 

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